Evidence map›Paper›PMID 20858236›Full record

ArticleBMC public health2010

Establishing a follow-up of the Swiss MONICA participants (1984-1993): record linkage with census and mortality data.

Matthias Bopp, Julia Braun, David Faeh, Felix Gutzwiller, Swiss National Cohort Study Group

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Article in BMC public health, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

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11citing papers in PubMed
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11 citing papers in PubMed.

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5 · Who and what money

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5 authors.

Matthias BoppInstitute of Social and Preventive Medicine, University of Zurich, Hirschengraben 84, 8001 Zurich, Switzerland. bopp@ifspm.uzh.ch
Julia Braun
David Faeh
Felix Gutzwiller
Swiss National Cohort Study Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo assess the feasibility and quality of an anonymous linkage of 1) MONICA (MONItoring of trends and determinants in CArdiovscular disease, three waves between 1984 and 1993) data with 2) census and mortality records of the Swiss National Cohort in order to establish a mortality follow-up until 2008. Many countries feature the defect of lacking general population cohorts because they have missed to provide for follow-up information of health surveys.

methodsRecord linkage procedures were used in a multi-step approach. Kaplan-Meier curves from our data were contrasted with the survival probabilities expected from life tables for the general population, age-standardized mortality rates from our data with those derived from official cross-sectional mortality data. Cox regression models were fit to investigate the influence of covariates on survival.

results97.8% of the eligible 10,160 participants (25-74y at baseline) could be linked to a census (1990: 9,737; 2000: 8,749), mortality (1,526, 1984-2008) and/or emigration record (320, 1990-2008). Linkage success did not differ by any key study characteristic. Results of survival analyses were robust to linkage step or certainty of a correct link. Loss to follow-up between 1990 and 2000 amounted to 4.7%. MONICA participants had lower mortality than the general population, but similar mortality patterns, (e.g. variation by educational level, marital status or region).

conclusionsUsing anonymized census and death records allowed an almost complete mortality follow-up of MONICA study participants of up to 25 years. Lower mortality compared to the general population was in line with a presumable 'healthy participant' selection in the original MONICA study. Apart from that, the derived data set reproduced known mortality patterns and showed only negligible potential for selection bias introduced by the linkage process. Anonymous record linkage was feasible and provided robust results. It can thus provide valuable information, when no cohort study is available.

Indexed as

CensusesMortalityAdultAgedConfidentialityCross-Sectional StudiesFeasibility StudiesFemaleFollow-Up StudiesHumansMaleMedical Record LinkageMiddle AgedProportional Hazards ModelsSurvival AnalysisSwitzerland

Identifiers

PMID20858236
PMCPMC2955001

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