ArticleNeuropsychiatric disease and treatment2010
Management of depression in elderly stroke patients.
Article in Neuropsychiatric disease and treatment, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 3 of them syntheses that pooled it.
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Who cites it
30 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Effect of nonpharmacological interventions on poststroke depression: a network meta-analysis.Frontiers in neurology · 2024Pooled it
- Role of social support in poststroke depression: A meta-analysis.Frontiers in psychiatry · 2022Pooled it
- Effectiveness of non-pharmacological interventions for treating post-stroke depressive symptoms: Systematic review and meta-analysis of randomized controlled trials.Topics in stroke rehabilitation · 2021Pooled it
- Effectiveness of group acceptance and commitment therapy in treating depression for acute stroke patients.Brain and behavior · 2023Trial
- Influence of an Aquatic Therapy Program on Perceived Pain, Stress, and Quality of Life in Chronic Stroke Patients: A Randomized Trial.International journal of environmental research and public health · 2020Trial
- Article
- Cardiac history and post-stroke depression association in Chinese stroke survivors: a cross sectional study.Scientific reports · 2025Article
- Advancing Post-Stroke Depression Research: Insights from Murine Models and Behavioral Analyses.Life (Basel, Switzerland) · 2024Review
- Integrative-interpersonal dynamic therapy for poststroke depression (INID): study protocol of a randomised controlled pilot trial.BMJ open · 2023Article
- Rest-Activity Rhythm Characteristics Associated With Depression Symptoms in Stroke Survivors.Archives of physical medicine and rehabilitation · 2023Observational
- Article
- Post-Stroke Depression: Prevalence, Associated Factors, and Relationship to Disability in a Tertiary Care Center in Sri Lanka.Journal of neurosciences in rural practice · 2022Article
- Predictors of Post-stroke Cognition Among Geriatric Patients: The Role of Demographics, Pre-stroke Cognition, and Trajectories of Depression.Frontiers in psychology · 2021Article
- Complementary and alternative therapies for poststroke depression: A protocol for systematic review and network meta-analysis.Medicine · 2020Article
- Dimensions of Poststroke Depression and Neuropsychological Deficits in Older Adults.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2020Article
- Neuropsychological Deficits Chronically Developed after Focal Ischemic Stroke and Beneficial Effects of Pharmacological Hypothermia in the Mouse.Aging and disease · 2020Article
- Prevalence, patterns and predictors of depression treatment among community-dwelling older adults with stroke in the United States: a cross sectional study.BMC psychiatry · 2018Article
- Efficacy and tolerability of pharmacotherapy for post-stroke depression: a network meta-analysis.Oncotarget · 2018Article
- Combining therapeutic approaches: rTMS and aerobic exercise in post-stroke depression: a case series.Topics in stroke rehabilitation · 2018Article
- A Combination of Three Repurposed Drugs Administered at Reperfusion as a Promising Therapy for Postischemic Brain Injury.Translational stroke research · 2017Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Poststroke depression (PSD) in elderly patients has been considered the most common neuropsychiatric consequence of stroke up to 6-24 months after stroke onset. When depression appears within days after stroke onset, it is likely to remit, whereas depression at 3 months is likely to be sustained for 1 year. One of the major problems posed by elderly stroke patients is how to identify and optimally manage PSD. This review provides insight to identification and management of depression in elderly stroke patients. Depression following stroke is less likely to include dysphoria and more likely characterized by vegetative signs and symptoms compared with other forms of late-life depression, and clinicians should rely more on nonsomatic symptoms rather than somatic symptoms. Evaluation and diagnosis of depression among elderly stroke patients are more complex due to vague symptoms of depression, overlapping signs and symptoms of stroke and depression, lack of properly trained health care personnel, and insufficient assessment tools for proper diagnosis. Major goals of treatment are to reduce depressive symptoms, improve mood and quality of life, and reduce the risk of medical complications including relapse. Antidepressants (ADs) are generally not indicated in mild forms because the balance of benefit and risk is not satisfactory in elderly stroke patients. Selective serotonin reuptake inhibitors are the first choice of PSD treatment in elderly patients due to their lower potential for drug interaction and side effects, which are more common with tricyclic ADs. Recently, stimulant medications have emerged as promising new therapeutic interventions for PSD and are now the subject of rigorous clinical trials. Cognitive behavioral therapy can also be useful, and electroconvulsive therapy is available for patients with severe refractory PSD.
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