Evidence map›Paper›PMID 20856792›Full record

ArticlePloS one2010

Social network sensors for early detection of contagious outbreaks.

Nicholas A Christakis, James H Fowler

Abstract read
In one paragraph

Article in PloS one, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers.

0numbers the graph read from it
0cells of the map it votes in
149citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

149 citing papers in PubMed.

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  11. Causal inference over stochastic networks.Journal of the Royal Statistical Society. Series A, (Statistics in Society) · 2024
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  18. Causal Inference for Social Network Data.Journal of the American Statistical Association · 2024
    Article
  19. The enmity paradox.Scientific reports · 2023
    Article
  20. Article

89 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Nicholas A ChristakisFaculty of Arts & Sciences, Harvard University, Boston, Massachusetts, United States of America. christakis@hcp.med.harvard.edu
James H Fowler

Funding

TR&D 3 - Network Guided Machine LearningP41GM103504 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BADER, GARY D. · 2012 to 2024
$17.3M
The Spread of Health Behaviors in the Framingham Heart Study Social NetworkP01AG031093 · NIA · YALE UNIVERSITY · PI CHRISTAKIS, NICHOLAS A · 2008 to 2012
$10.7M
NIA NIH HHS P-01 AG-031093NIA NIH HHS P01 AG031093NIGMS NIH HHS P41 GM103504
6 · The paper itself

Abstract

Current methods for the detection of contagious outbreaks give contemporaneous information about the course of an epidemic at best. It is known that individuals near the center of a social network are likely to be infected sooner during the course of an outbreak, on average, than those at the periphery. Unfortunately, mapping a whole network to identify central individuals who might be monitored for infection is typically very difficult. We propose an alternative strategy that does not require ascertainment of global network structure, namely, simply monitoring the friends of randomly selected individuals. Such individuals are known to be more central. To evaluate whether such a friend group could indeed provide early detection, we studied a flu outbreak at Harvard College in late 2009. We followed 744 students who were either members of a group of randomly chosen individuals or a group of their friends. Based on clinical diagnoses, the progression of the epidemic in the friend group occurred 13.9 days (95% C.I. 9.9-16.6) in advance of the randomly chosen group (i.e., the population as a whole). The friend group also showed a significant lead time (p<0.05) on day 16 of the epidemic, a full 46 days before the peak in daily incidence in the population as a whole. This sensor method could provide significant additional time to react to epidemics in small or large populations under surveillance. The amount of lead time will depend on features of the outbreak and the network at hand. The method could in principle be generalized to other biological, psychological, informational, or behavioral contagions that spread in networks.

Indexed as

Disease OutbreaksSocial SupportEarly DiagnosisEpidemicsFemaleHumansInfluenza, HumanMaleYoung Adult

Identifiers

PMID20856792
PMCPMC2939797

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.