Evidence map›Paper›PMID 20856603›Full record

ArticleNeuropsychiatric disease and treatment2010

Relationship between hair cortisol concentrations and depressive symptoms in patients with coronary artery disease.

Yekta Dowlati, Nathan Herrmann, Walter Swardfager, Steven Thomson, Paul I Oh, Stan Van Uum, Gideon Koren, Krista L Lanctôt

Open access · greenAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 2 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Chronic adrenocortical activity and onset of Takotsubo syndrome.European journal of cardiovascular nursing · 2026
    Observational
  6. Article
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  12. Parity-related variation in cortisol concentrations in hair during pregnancy.BJOG : an international journal of obstetrics and gynaecology · 2021
    Article
  13. Article
  14. Methods of Assessment of the Welfare of Shelter Cats: A Review.Animals : an open access journal from MDPI · 2020
    Review
  15. Article
  16. Review
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  18. Using path analysis to investigate the relationships between depression, anxiety, and health-related quality of life among patients with coronary artery disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2019
    Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yekta DowlatiDepartments of Pharmacology and Toxicology and Psychiatry, University of Toronto, Canada.
Nathan Herrmann
Walter Swardfager
Steven Thomson
Paul I Oh
Stan Van Uum
Gideon Koren
Krista L Lanctôt
University of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveConcentrations of cortisol in hair, a novel marker of longer-term cortisol status, were compared in depressed versus nondepressed patients with coronary artery disease (CAD).

methods20 mg hair samples of 3 cm length were collected from 121 patients attending a cardiac rehabilitation program, 34 of whom suffered from depressive symptoms.

resultsControlling for age, gender, coronary artery bypass grafting, history of depression, and time since most recent acute coronary syndrome, cortisol concentrations (P = 0.162) did not predict severity of depression. Younger age (P = 0.003) was a significant predictor of depressive symptoms. Perceived stress was not associated with long-term cortisol concentrations (P = 0.161).

conclusionsCortisol concentrations in hair do not predict depressive symptoms in CAD patients attending cardiac rehabilitation.

Indexed as

coronary artery diseasecortisoldepressionhair

Identifiers

PMID20856603
PMCPMC2938288
OpenAlexW2109699728

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.