ArticleThe Journal of physiology2010
Comparison of synaptic transmission and plasticity between sensory and cortical synapses on relay neurons in the ventrobasal nucleus of the rat thalamus.
Article in The Journal of physiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 23 citations in OpenAlex.
- Pharmacological and Physiological Characteristics of Synaptic Transmissions From the Medial Prefrontal Cortex Onto Noradrenergic Neurons and Inhibitory Interneurons in the Mouse Locus Coeruleus.The European journal of neuroscience · 2026Article
- Persistent input- and cell-type-specific synaptic alterations in the somatosensory thalamus of Dravet syndrome mice.Journal of neurophysiology · 2026Article
- The Molecular Machinery of Synaptic Plasticity and Its Potential Role in the Aetiology of Schizophrenia.Molecular neurobiology · 2026Review
- Circuit-selective pharmacological targeting of prefrontal cortex-projecting locus coeruleus neurons drives antinociception.Cell reports · 2025Article
- Input-Specific Localization of NMDA Receptor GluN2 Subunits in Thalamocortical Neurons.Journal of neurochemistry · 2025Article
- Input-specific localization of NMDA receptor GluN2 subunits in thalamocortical neurons.bioRxiv : the preprint server for biology · 2024Article
- Ventral posterolateral and ventral posteromedial thalamocortical neurons have distinct physiological properties.Journal of neurophysiology · 2023Article
- Article
- Dual function of thalamic low-vigilance state oscillations: rhythm-regulation and plasticity.Nature reviews. Neuroscience · 2018Review
- Form and Function of Sleep Spindles across the Lifespan.Neural plasticity · 2016Review
- Article
- L-type calcium channel-dependent inhibitory plasticity in the thalamus.Journal of neurophysiology · 2014Review
- Local changes in neocortical circuit dynamics coincide with the spread of seizures to thalamus in a model of epilepsy.Frontiers in neural circuits · 2014Article
- Non-Hebbian long-term potentiation of inhibitory synapses in the thalamus.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- Predictions not commands: active inference in the motor system.Brain structure & function · 2013Review
- GABAB Receptors Regulate Extrasynaptic GABAA Receptors.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Article
- T-type calcium channels consolidate tonic action potential output of thalamic neurons to neocortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- ERK, synaptic plasticity and acid-induced muscle pain.Communicative & integrative biology · 2011Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Relay neurons in the ventrobasal nucleus of the thalamus transmit somatosensory information to the cerebral cortex and receive sensory and cortical (feedback) synaptic inputs via, respectively, medial lemniscal (ML) and corticothalamic (CT) fibres. Here, we report that calcium-permeable AMPA receptors are expressed at CT synapses, but not ML synapses, and that the NMDA receptor (NMDAR)-mediated/non-NMDAR-mediated synaptic current ratio is significantly larger at CT synapses than at ML synapses. Moreover, NMDAR-dependent LTP and L-type voltage-gated calcium channel-dependent LTD are readily induced at CT synapses, but not ML synapses. In particular, LTD of CT synaptic transmission is induced by spiking of postsynaptic relay neurons in continuous mode, but not burst mode, in current-clamp recordings. These results show that the strength of the cortical input to thalamic relay neurons is selectively subjected to use-dependent modification, which could be a mechanism for regulation of thalamocortical-corticothalamic interactions and the underlying sensory processing.
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