Evidence map›Paper›PMID 20855111›Full record

ReviewThe Journal of allergy and clinical immunology2011

A call for action: Comparative effectiveness research in asthma.

Jerry A Krishnan, Michael Schatz, Andrea J Apter

Registry-linked trialAbstract readReview
In one paragraph

Review in The Journal of allergy and clinical immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01128348 (A Patient Advocate and Literacy-Based Treatment of Asthma), which is not on this map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
17.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01128348 nacompletednot on this map

A Patient Advocate and Literacy-Based Treatment of Asthma

TypeinterventionalSponsorUniversity of PennsylvaniaRan2009 to 2011Enrolled100ConditionsAsthmaArmspatient advocate
3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Eszopiclone for insomnia.The Cochrane database of systematic reviews · 2018
    Pooled it
  2. Trial
  3. Trial
  4. Article
  5. Review
  6. Article
  7. Observational
  8. Management of asthma in the elderly patient.Clinical interventions in aging · 2013
    Review
  9. Inhaled corticosteroids used for the control of asthma in a "real-life" setting do not affect linear growth velocity in prepubertal children.Medical science monitor : international medical journal of experimental and clinical research · 2012
    Article
  10. Review
  11. Article
  12. Advancing asthma care: the glass is only half full!The Journal of allergy and clinical immunology · 2011
    Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 3 institutions in 1 country.

Jerry A KrishnanDepartment of Medicine, Section of Pulmonary and Critical Care, University of Chicago, Chicago, Ill. 60637, USA. jkrishna@medicine.bsd.uchicago.edu
Michael Schatz
Andrea J Apter
Kaiser Permanente San Diego Medical Center · USUniversity of Chicago · USUniversity of Pennsylvania · US

Funding

CONCERT-Clinical Effectiveness Research (CONCERT-CER)RC2HL101618 · NHLBI · UNIVERSITY OF CHICAGO · PI AU, DAVID H, CARSON, SHANNON S · 2009 to 2010
$7.4M
Individualized Interventions to Improve Asthma AdherenceR01HL073932 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI APTER, ANDREA J. · 2005 to 2009
$3.6M
A Patient Advocate and Literacy-Based Treatment of AsthmaRC1HL099612 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI APTER, ANDREA J. · 2009 to 2010
$1.0M
Literacy and improving patient-clinician encounters for AsthmaK02HL088469 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI APTER, ANDREA J. · 2007 to 2011
$526k
Setting effectiveness and translational research priorities to improve COPD careR13HS017894 · AHRQ · UNIVERSITY OF CHICAGO · PI KRISHNAN, JERRY A. · 2008 to 2009
$200k
AHRQ HHS HS017894AHRQ HHS R13 HS017894NHLBI NIH HHS HL073932NHLBI NIH HHS HL088469NHLBI NIH HHS HL099612NHLBI NIH HHS HL101618NHLBI NIH HHS K02 HL088469NHLBI NIH HHS R01 HL073932NHLBI NIH HHS RC1 HL099612NHLBI NIH HHS RC2 HL101618
6 · The paper itself

Abstract

Comparative effectiveness research (CER) has received considerable research attention in recent months, and efforts to promote CER are part of the newly enacted Patient Protection and Affordable Care Act. In this article we define CER and how it complements traditional efficacy research in asthma and discuss how CER can help provide the basis for rational decision making about the care of individual patients with asthma and how best to deliver this care in real-world settings. We present information about the challenges and opportunities to conduct CER, including enhanced patient registries for observational CER and effectiveness trials (also called pragmatic trials). We discuss the urgent need to define the appropriate methodologies for CER and to develop and prioritize a research agenda for CER studies in asthmatic subjects with the help of a diverse group of stakeholders.

Indexed as

Anti-Asthmatic AgentsAsthmaComparative Effectiveness ResearchHumansPatient Protection and Affordable Care ActRandomized Controlled Trials as TopicUnited StatesAnti-Asthmatic Agents

Identifiers

PMID20855111
PMCPMC3017678
OpenAlexW2017226579

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.