ArticleHuman brain mapping2011
Structural covariance in the cortex of very preterm adolescents: a voxel-based morphometry study.
Article in Human brain mapping, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 46 citations in OpenAlex.
- Decreased amygdala volume in adults after premature birth.Scientific reports · 2021Trial
- Trial
- Early life factors and structural brain network in children with overweight/obesity: The ActiveBrains project.Pediatric research · 2024Article
- Early-life stress exposure and large-scale covariance brain networks in extremely preterm-born infants.Translational psychiatry · 2022Article
- Distinct effects of prematurity on MRI metrics of brain functional connectivity, activity, and structure: Univariate and multivariate analyses.Human brain mapping · 2021Article
- Anti-Inflammatory Therapies for Treatment of Inflammation-Related Preterm Brain Injury.International journal of molecular sciences · 2021Review
- Within amygdala: Basolateral parts are selectively impaired in premature-born adults.NeuroImage. Clinical · 2021Article
- Psychosocial and Neurobiological Vulnerabilities of the Hospitalized Preterm Infant and Relevant Non-pharmacological Pain Mitigation Strategies.Frontiers in pediatrics · 2021Review
- Disruption and Compensation of Sulcation-based Covariance Networks in Neonatal Brain Growth after Perinatal Injury.Cerebral cortex (New York, N.Y. : 1991) · 2020Article
- A machine learning investigation of volumetric and functional MRI abnormalities in adults born preterm.Human brain mapping · 2019Article
- Parcellation of the human hippocampus based on gray matter volume covariance: Replicable results on healthy young adults.Human brain mapping · 2019Article
- Gestational Age is Dimensionally Associated with Structural Brain Network Abnormalities Across Development.Cerebral cortex (New York, N.Y. : 1991) · 2019Article
- Language Network Function in Young Children Born Very Preterm.Frontiers in human neuroscience · 2018Article
- Volumetric grey matter alterations in adolescents and adults born very preterm suggest accelerated brain maturation.NeuroImage · 2017Article
- Familial and environmental influences on brain volumes in twins with schizophrenia.Journal of psychiatry & neuroscience : JPN · 2017Article
- Alterations in Anatomical Covariance in the Prematurely Born.Cerebral cortex (New York, N.Y. : 1991) · 2017Article
- Language at rest: A longitudinal study of intrinsic functional connectivity in preterm children.NeuroImage. Clinical · 2016Article
- Fibromyalgia is characterized by altered frontal and cerebellar structural covariance brain networks.NeuroImage. Clinical · 2015Article
- Long-term neurobiological consequences of early postnatal hCMV-infection in former preterms: a functional MRI study.Human brain mapping · 2014Article
- Early repetitive pain in preterm infants in relation to the developing brain.Pain management · 2014Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
On the basis of findings in normative samples that different cortical brain regions covary in gray matter volume, most likely as a result of mutually trophic influences during cortical development, we aimed to study whether patterns of covariation in regional gray matter, i.e., structural covariance, differed between adolescents who were born very preterm and full-term controls. Optimized voxel-based morphometry was used to study structural magnetic resonance imaging scans from 218 very preterm adolescents (gestational age <33 weeks) and 127 controls at 14-15 years of age. Local gray matter volumes were obtained for 18 regions of interest involved in sensorimotor and higher-order cognitive functions. These were then used to predict local volumes in the remaining areas of the cortex, with total gray matter volume, age and gender used as confounding variables. Very preterm adolescents compared with controls demonstrated differential (i.e., both increased and decreased) structural covariance between medial, frontal and cingulate gyri, caudate nucleus, thalamus, primary visual cortex, cerebellum and several other cortical and subcortical regions of the cortex. These findings support previous research indicating that preterm birth is associated with altered cortical development, and suggest that developmental changes in one brain region may result in a cascade of alterations in multiple regions.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.