ArticleMolecular imaging and biology2011
Determinants of physiologic 18F-FDG uptake in brown adipose tissue in sequential PET/CT examinations.
Article in Molecular imaging and biology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 50 citations in OpenAlex.
- No evidence of brown adipose tissue activation after 24 weeks of supervised exercise training in young sedentary adults in the ACTIBATE randomized controlled trial.Nature communications · 2022Trial
- Brown Adipose Tissue in Breast Cancer Evaluated by [Molecular imaging and biology · 2020Trial
- Effect of β3-adrenergic receptor agonists on [EJNMMI research · 2025Article
- Treatment Resulting Changes in Volumes of High-International journal of molecular sciences · 2023Article
- Brown adipose tissue uptake of triglyceride-rich lipoprotein-derived fatty acids in diabetic or obese mice under different temperature conditions.EJNMMI research · 2020Article
- Association between brown adipose tissue and bone mineral density in humans.International journal of obesity (2005) · 2019Article
- Implication of atypical supraclavicular F18-fluorodeoxyglucose uptake in patients with breast cancer: Association between brown adipose tissue and breast cancer.Oncology letters · 2017Article
- Factors influencing brown fat activation in FDG PET/CT: a retrospective analysis of 15,000+ cases.The British journal of radiology · 2017Article
- Brown fat depots in adult humans remain static in their locations on PET/CT despite changes in seasonality.Physiological reports · 2017Article
- Lack of Seasonal Differences in Basal Metabolic Rate in Humans: A Cross-Sectional Study.Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme · 2017Article
- Imaging of Brown Adipose Tissue: State of the Art.Radiology · 2016Review
- Renaissance of brown adipose tissue research: integrating the old and new.International journal of obesity supplements · 2015Review
- Metabolic activity of the tongue in obstructive sleep apnea. A novel application of FDG positron emission tomography imaging.American journal of respiratory and critical care medicine · 2014Article
- Molecular imaging of brown adipose tissue in health and disease.European journal of nuclear medicine and molecular imaging · 2014Review
- Changes in brown adipose tissue in boys and girls during childhood and puberty.The Journal of pediatrics · 2012Article
- The relationship between brown adipose tissue activity and neoplastic status: an (18)F-FDG PET/CT study in the tropics.Lipids in health and disease · 2011Article
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Authors and funding
9 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe aim of this study was to assess independent predictors of 2-deoxy-2-[(18)F]fluoro-D-glucose ((18)F-FDG) uptake in brown adipose tissue (BAT) in patients undergoing repeated positron emission tomography (PET)/computed tomography (CT) scans. PROCEDURES: Eight hundred forty-eight (mean age 50.9 ± 16 years) patients in whom PET/CT scan was repeated (mean interval 5 ± 1.5 months) constituted the study group. (18)F-FDG uptake in characteristic areas of BAT, with CT density of adipose tissue, greater than background soft-tissue activity was considered as evidence of BAT uptake. Both distribution and maximum standardized uptake values (SUVmax) were registered. Clinical and anamnestic data were collected for each patient.
results(18)F-FDG uptake in BAT was present in 8.6% patients at first scan. Independent predictors of presence of uptake were age (younger), gender (female), body mass index (lower), and maximum outdoor temperature (lower). Age was the only independent predictor of BAT (18)F-FDG uptake distribution, while SUVmax was related to both age and outdoor temperature. Independent determinants of persistence of BAT (18)F-FDG uptake at second PET/CT were outdoor temperature at time of second scan and extension of metabolically active BAT at first scan.
conclusionsAge, body mass index, and outdoor temperature are significant determinants of BAT evidence at (18)F-FDG PET/CT. Moreover, extension of BAT and outdoor temperature are the strongest determinants of persistence of BAT evidence on (18)F-FDG PET/CT in repeated scan.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.