ArticleBehavior genetics2011
Genome scan for spelling deficits: effects of verbal IQ on models of transmission and trait gene localization.
Article in Behavior genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed.
- Targeted analysis of dyslexia-associated regions on chromosomes 6, 12 and 15 in large multigenerational cohorts.PloS one · 2025Article
- Heritability and longitudinal outcomes of spelling skills in individuals with histories of early speech and language disorders.Learning and individual differences · 2018Article
- Self-government of complex reading and writing brains informed by cingulo-opercular network for adaptive control and working memory components for language learning.Journal of systems and integrative neuroscience · 2017Article
- Differential Diagnosis of Dysgraphia, Dyslexia, and OWL LD: Behavioral and Neuroimaging Evidence.Reading and writing · 2015Article
- Genome scan for cognitive trait loci of dyslexia: Rapid naming and rapid switching of letters, numbers, and colors.American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics · 2014Article
- Differences between Children with Dyslexia Who Are and Are Not Gifted in Verbal Reasoning.The gifted child quarterly · 2013Article
- The genetics of reading disabilities: from phenotypes to candidate genes.Frontiers in psychology · 2012Article
- Relative burden of large CNVs on a range of neurodevelopmental phenotypes.PLoS genetics · 2011Article
- Moving closer to a public health model of language and learning disabilities: the role of genetics and the search for etiologies.Behavior genetics · 2011Review
- In search of the perfect phenotype: an analysis of linkage and association studies of reading and reading-related processes.Behavior genetics · 2011Review
- Evidence-Based Reading and Writing Assessment for Dyslexia in Adolescents and Young Adults.Learning disabilities (Pittsburgh, Pa.)Article
- The Role of Neural and Genetic Processes in Learning to Read and Specific Reading Disabilities: Implications for Instruction.Reading research quarterlyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Dyslexia is a complex learning disability with evidence for a genetic basis. Strategies that may be useful for dissecting its genetic basis include the study of component phenotypes, which may simplify the underlying genetic complexity, and use of an analytic approach that accounts for the multilocus nature of the trait to guide the investigation and increase power to detect individual loci. Here we present results of a genetic analysis of spelling disability as a component phenotype. Spelling disability is informative in analysis of extended pedigrees because it persists into adulthood. We show that a small number of hypothesized loci are sufficient to explain the inheritance of the trait in our sample, and that each of these loci maps to one of four genomic regions. Individual trait models and locations are a function of whether a verbal IQ adjustment is included, suggesting mediation through both IQ-related and unrelated pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.