Evidence map›Paper›PMID 20851211›Full record

ReviewClinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association2010

Liver disease in the HIV-infected individual.

Jennifer C Price, Chloe L Thio

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05023044 (Nonalcoholic Fatty Liver Disease In Persons Living With HIV Database Study), which is not on this map. Cited by 117 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
117citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05023044 active not recruitingnot on this mapstarted 2022, after this paper: background citation

Nonalcoholic Fatty Liver Disease In Persons Living With HIV Database Study

TypeobservationalSponsorJohns Hopkins UniversityRan2022 to 2031Enrolled400ConditionsNAFLD, NASH - Nonalcoholic Steatohepatitis, Hiv
3 · Its place in the literature

Who cites it

117 citing papers in PubMed, 3 syntheses or guidelines pooled it, 197 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Trial
  5. Trial
  6. Sofosbuvir and Velpatasvir for the Treatment of Hepatitis C Virus in Patients Coinfected With Human Immunodeficiency Virus Type 1: An Open-Label, Phase 3 Study.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2017
    Trial
  7. Article
  8. Article
  9. Review
  10. Article
  11. Article
  12. Article
  13. Prevalence and Spectrum of Chronic Liver Disease Among Patients Seeking Health Care in Ghana.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review

57 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Jennifer C PriceDepartment of Medicine, Johns Hopkins School of Medicine, Baltimore, Maryland 21287, USA. jcohen@jhmi.edu
Chloe L Thio
Johns Hopkins Medicine · USJohns Hopkins University · US

Funding

Institute for Clinical and Translational Research (KL2)KL2RR025006 · NCRR · JOHNS HOPKINS UNIVERSITY · PI FORD, DANIEL ERNEST · 2007 to 2011
$12.9M
Liver Disease and HIV-HBV Coinfection in the HAART eraR01AI060449 · NIAID · JOHNS HOPKINS UNIVERSITY · PI THIO, CHLOE L · 2004 to 2008
$3.0M
Hepatitis B treatment and HIV Infection in resources limited settingsR01AI071820 · NIAID · JOHNS HOPKINS UNIVERSITY · PI THIO, CHLOE L · 2006 to 2010
$1.9M
NCRR NIH HHS 1KL2RR025006-01NCRR NIH HHS KL2 RR025006NIAID NIH HHS R01 AI060449NIAID NIH HHS R01 AI071820
6 · The paper itself

Abstract

Since the advent of effective antiretroviral therapy (ART) for human immunodeficiency virus-1 (HIV), there has been a substantial decrease in deaths related to acquired immunodeficiency syndrome (AIDS). However, in the ART era, liver disease is now the most common non-AIDS-related cause of death among HIV-infected patients, accounting for 14%-18% of all deaths in this population and almost half of deaths among hospitalized HIV-infected patients. Just as the burden of non-AIDS morbidity and mortality has changed in the ART era, the types of liver disease the clinician is likely to encounter among these patients have changed as well. This review will discuss the causes of liver disease in the HIV-infected population in the ART era, including chronic hepatitis C virus, chronic hepatitis B virus, medication-related hepatotoxicity, alcohol abuse, nonalcoholic fatty liver disease, and AIDS-related liver diseases.

Indexed as

Anti-HIV AgentsAntiretroviral Therapy, Highly ActiveChemical and Drug Induced Liver InjuryFatty LiverHepatitis B, ChronicHepatitis C, ChronicHIV InfectionsHumansLiver DiseasesLiver Diseases, AlcoholicNon-alcoholic Fatty Liver DiseaseAnti-HIV Agents

Identifiers

PMID20851211
PMCPMC2997131
OpenAlexW2043684475

What OpenQuestion holds

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LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.