ReviewNeuroscience and biobehavioral reviews2011
Identifying key features of early stressful experiences that produce stress vulnerability and resilience in primates.
Review in Neuroscience and biobehavioral reviews, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
76 citing papers in PubMed, 188 citations in OpenAlex.
- When Does Stress Build Strength? Linking Stress Physiology to Resilience in the Age of Rapid Environmental Change.BioEssays : news and reviews in molecular, cellular and developmental biology · 2026Review
- Depression in Mature Male Rhesus Macaques (Macaca mulatta): Direct and Delayed Consequences of Deprivation.Bulletin of experimental biology and medicine · 2026Article
- Cognitive reserve and adaptive resilience: a conceptual analysis of a cross-species framework for neuropsychology and cognitive aging.Frontiers in psychology · 2026Review
- Adolescent stress exposure induces persistent, sex-specific cognitive deficits.Neurobiology of learning and memory · 2025Article
- Early positive tactile stimulation reverses the increase of anxiety and decrease of sociality induced by early chronic mechanical pain in mandarin voles.Integrative zoology · 2025Article
- Neighborhood Disadvantage and Parenting in Early Adolescence Predict Epigenetic Aging and Mortality Risk in Adulthood.Journal of youth and adolescence · 2024Article
- New policies on skin-to-skin contact warrant an oxytocin-based perspective on perinatal health care.Frontiers in psychology · 2024Article
- Tales from the life and lab of a female social neuroscientist.Comprehensive psychoneuroendocrinology · 2023Review
- Social contact from birth influences personality traits of group-housed dairy calves.JDS communications · 2023Article
- Responses to Reduced Feeding Frequency in Captive-Born Cheetahs (Animals : an open access journal from MDPI · 2023Article
- Resilience to depression: Implication for psychological vaccination.Frontiers in psychiatry · 2023Review
- Porcine blood cell and brain tissue energy metabolism: Effects of "early life stress".Frontiers in molecular biosciences · 2023Article
- Optimising Puppy Socialisation-Short- and Long-Term Effects of a Training Programme during the Early Socialisation Period.Animals : an open access journal from MDPI · 2022Article
- Preconception stress exposure from childhood to adolescence and birth outcomes: The impact of stress type, severity and consistency.Frontiers in reproductive health · 2022Article
- Capturing the dynamic nature of stress exposure in the Pittsburgh Girls Study.SSM - population health · 2021Article
- Phenotyping stress exposures related to perinatal health disparities.Developmental psychobiology · 2021Article
- Long-term effects of intermittent early life stress on primate prefrontal-subcortical functional connectivity.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2021Article
- Positive Human Contact and Housing Systems Impact the Responses of Piglets to Various Stressors.Animals : an open access journal from MDPI · 2021Article
- Childhood maltreatment interacts with hypothalamic-pituitary-adrenal axis negative feedback and major depression: effects on cognitive performance.European journal of psychotraumatology · 2021Article
- Assessing the sociability of former pet and entertainment chimpanzees by using multiplex networks.Scientific reports · 2020Article
16 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
This article examines the complex role of early stressful experiences in producing both vulnerability and resilience to later stress-related psychopathology in a variety of primate models of human development. Two types of models are reviewed: Parental Separation Models (e.g., isolate-rearing, peer-rearing, parental separations, and stress inoculation) and Maternal Behavior Models (e.g., foraging demands, variation in maternal style, and maternal abuse). Based on empirical evidence, it is argued that early life stress exposure does not increase adult vulnerability to stress-related psychopathology as a linear function, as is generally believed, but instead reflects a quadratic function. Features of early stress exposure including the type, duration, frequency, ecological validity, sensory modality, and developmental timing, within and between species, are identified to better understand how early stressful experiences alter neurobiological systems to produce such diverse developmental outcomes. This article concludes by identifying gaps in our current knowledge, providing directions for future research, and discussing the translational implications of these primate models for human development and psychopathology.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.