Evidence map›Paper›PMID 20851087›Full record

ArticleVaccine2010

Effectiveness of rotavirus vaccine in preventing hospitalization due to rotavirus gastroenteritis in young children in Connecticut, USA.

Sachin N Desai, Daina B Esposito, Eugene D Shapiro, Penelope H Dennehy, Marietta Vázquez

Abstract read
In one paragraph

Article in Vaccine, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
3.7field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Observational
  10. Rotavirus vaccines in routine use.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014
    Review
  11. Review
  12. Rotavirus vaccines: current status and future considerations.Human vaccines & immunotherapeutics · 2014
    Review
  13. Article
  14. Treatment and prevention of rotavirus infection in children.Current infectious disease reports · 2013
    Article
  15. Group A rotaviruses in children with gastroenteritis in a Canadian pediatric hospital: The prevaccine era.The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2013
    Article
  16. Article
  17. Article
  18. Effectiveness of rotavirus vaccine in preventing severe acute gastroenteritis in children.Canadian family physician Medecin de famille canadien · 2012
    Article
  19. The control of rotavirus gastroenteritis in the United States.Transactions of the American Clinical and Climatological Association · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Sachin N DesaiDepartment of Pediatrics, Yale University School of Medicine, New Haven, CT 06520-8264, USA.
Daina B Esposito
Eugene D Shapiro
Penelope H Dennehy
Marietta Vázquez
Yale University · USBrown University · US

Funding

YALE UNIVERSITY CLINICAL AND TRANSLATIONAL SCIENCE AWARD PROGRAMUL1RR024139 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$56.8M
Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
Yale University Clinical and Translational Science Award ProgramKL2RR024138 · NCRR · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2006 to 2011
$4.8M
Yale University Clinical and Translational Science Award ProgramKL2TR000140 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$2.9M
The Effectiveness of Vaccines in Clinical PracticeK24RR022477 · NCRR · YALE UNIVERSITY · PI SHAPIRO, EUGENE DAVID · 2006 to 2010
$760k
Epidemiology of human metapneumovirus(hMPV)infectionK23AI068280 · NIAID · YALE UNIVERSITY · PI VAZQUEZ, MARIETTA · 2005 to 2009
$677k
THE EFFECTIVENESS OF VACCINES IN CLINICAL PRACTICEK24AI001703 · NIAID · YALE UNIVERSITY · PI SHAPIRO, EUGENE DAVID · 2000 to 2004
$544k
NCATS NIH HHS KL2 TR000140NCATS NIH HHS UL1 TR000142NCRR NIH HHS K24 RR022477NCRR NIH HHS KL2 RR024138NCRR NIH HHS KL2RR024138NCRR NIH HHS UL1 RR024139NIAID NIH HHS K23 AI068280NIAID NIH HHS K23 AI68280NIAID NIH HHS K24 AI001703
6 · The paper itself

Abstract

Rotavirus vaccine was recommended for use in US infants to prevent rotavirus gastroenteritis (RGE) in February 2006. This matched case control study assessed the effectiveness of rotavirus vaccine in preventing hospitalization of young. Cases were vaccine-eligible children 8 weeks-3 years of age, hospitalized due to laboratory-confirmed RGE. Cases (n=42) were matched to 2 control groups: (a) hospitalized controls (n=80): children hospitalized for reasons other than RGE, matched to the cases by age and time of presentation and (b) community controls (n=73): non-hospitalized children matched by age and medical practice. Adjusted vaccine effectiveness against hospitalization with RGE in vaccine eligible children receiving at least one dose of vaccine was 94.3% (95% C.I.: 55.4%-99.3%; p=0.006) for hospitalized controls and 96.9% (95% C.I.: 59.4%-99.8%; p=0.008) for community controls.

Indexed as

HospitalizationCase-Control StudiesChild, PreschoolConnecticutFemaleGastroenteritisHumansInfantMaleRotavirus InfectionsRotavirus VaccinesRotavirus Vaccines

Identifiers

PMID20851087
PMCPMC5127692
OpenAlexW2009614436

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.