Evidence map›Paper›PMID 20850450›Full record

ArticleJournal of molecular and cellular cardiology2010

How does the shape of the cardiac action potential control calcium signaling and contraction in the heart?

Luis F Santana, Edward P Cheng, W Jonathan Lederer

Abstract readEditorial
In one paragraph

Article in Journal of molecular and cellular cardiology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
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  5. Article
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  7. Article
  8. Review
  9. Article
  10. [How to: clinical use of antiarrhythmic drugs].Herzschrittmachertherapie & Elektrophysiologie · 2023
    Review
  11. The Role of CaBiomolecules · 2022
    Article
  12. Article
  13. Review
  14. Intrinsically Conductive Polymers for Striated Cardiac Muscle Repair.International journal of molecular sciences · 2021
    Review
  15. Review
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Luis F Santana
Edward P Cheng
W Jonathan Lederer

Funding

Molecular Basis of Sudden Cardiac DeathP01HL067849 · NHLBI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI D'ARMIENTO, JEANINE M · 2001 to 2011
$15.0M
NFAT-induced Regional Variations in Kv4 Channel Expression in HeartR01HL085686 · NHLBI · UNIVERSITY OF WASHINGTON · PI SANTANA, LUIS F · 2007 to 2020
$5.7M
Calcium Entrained ArrhythmiasR01HL105239 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JAFRI, MOHSIN SALEET, LEDERER, WILLIAM JONATHAN · 2011 to 2015
$4.9M
Strain Controlled LVAD Unloading and Post MI RemodelingR01HL081106 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI GRIFFITH, BARTLEY P · 2006 to 2010
$3.4M
Stretch-Dependent Calcium Signaling in HeartR01HL106059 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI LEDERER, WILLIAM JONATHAN · 2011 to 2014
$1.5M
NHLBI NIH HHS HL081106NHLBI NIH HHS HL085686NHLBI NIH HHS P01 HL067849NHLBI NIH HHS P01 HL67849NHLBI NIH HHS R01 HL081106NHLBI NIH HHS R01 HL085686NHLBI NIH HHS R01 HL105239NHLBI NIH HHS R01 HL106059
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Calcium SignalingAction PotentialsAdultAnimalsCalcium ChannelsDogsExcitation Contraction CouplingHeartHeart FailureHumansMyocardial ContractionMyocytes, CardiacRatsCalcium Channels

Identifiers

PMID20850450
PMCPMC3623268

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.