Evidence map›Paper›PMID 20850361›Full record

ArticleJournal of magnetic resonance (San Diego, Calif. : 1997)2010

In vivo multisite oximetry using EPR-NMR coimaging.

R Ahmad, G Caia, L C Potter, S Petryakov, P Kuppusamy, J L Zweier

Open access · greenAbstract read
In one paragraph

Article in Journal of magnetic resonance (San Diego, Calif. : 1997), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.9field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

  1. Reconfigurable animal bed-EPR resonator assembly for multimodal co-registration.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Spectral modeling for accelerated pH spectroscopy using EPR.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2012
    Article
  9. Multisite EPR oximetry from multiple quadrature harmonics.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

R AhmadCenter for Biomedical EPR Spectroscopy and Imaging, Davis Heart and Lung Research Institute, Department of Internal Medicine, The Ohio State University, Columbus, OH 43210, USA. rizwan.ahmad@osumc.edu
G Caia
L C Potter
S Petryakov
P Kuppusamy
J L Zweier
The Ohio State University · US

Funding

Proton Electron Double Resonance Imaging (PEDRI) of Free RadicalsR01EB004900 · NIBIB · OHIO STATE UNIVERSITY · PI ZWEIER, JAY LOUIS · 2005 to 2008
$3.4M
In Vivo EPR/NMR Co-Imaging of Free RadicalsR01EB000890 · NIBIB · OHIO STATE UNIVERSITY · PI ZWEIER, JAY LOUIS · 2002 to 2005
$2.9M
Sparse multispectral processing for accelerated EPR oximetry in three dimensionsR21EB008836 · NIBIB · OHIO STATE UNIVERSITY · PI POTTER, LEE C. · 2009 to 2010
$284k
NIBIB NIH HHS EB008836NIBIB NIH HHS EB0890NIBIB NIH HHS EB4900NIBIB NIH HHS R01 EB000890NIBIB NIH HHS R01 EB004900NIBIB NIH HHS R21 EB008836
6 · The paper itself

Abstract

Coimaging employing electron paramagnetic resonance (EPR) imaging and MRI is used for rapid in vivo oximetry conducted simultaneously across multiple organs of a mouse. A recently developed hybrid EPR-NMR coimaging instrument is used for both EPR and NMR measurements. Oxygen sensitive particulate EPR probe is implanted in small localized pockets, called sites, across multiple regions of a live mouse. Three dimensional MRI is used to generate anatomic visualization, providing precise locations of implant sites. The pO₂ values, one for every site, are then estimated from EPR measurements. To account for radio frequency (RF) phase inhomogeneities inside a large resonator carrying a lossy sample, a generalization of an existing EPR data model is proposed. Utilization of known spectral lineshape, sparse distribution, and known site locations reduce the EPR data collection by more than an order of magnitude over a conventional spectral-spatial imaging, enhancing the feasibility of in vivo EPR oximetry for clinically relevant models.

Indexed as

AlgorithmsAnimalsComputer SimulationData Interpretation, StatisticalElectron Spin Resonance SpectroscopyIndolesMagnetic Resonance ImagingMagnetic Resonance SpectroscopyMiceOrganometallic CompoundsOximetryPhantoms, ImagingSpin LabelsIndoleslithium phthalocyanineOrganometallic CompoundsSpin Labels

Identifiers

PMID20850361
PMCPMC2956866
OpenAlexW2036085789

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.