Evidence map›Paper›PMID 20849976›Full record

ReviewMicrobes and infection2010

Impact of aging on viral infections.

Jin Leng, Daniel R Goldstein

Open access · greenAbstract readReview
In one paragraph

Review in Microbes and infection, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it, 78 citations in OpenAlex.

  1. Pooled it
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  3. Review
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  8. Host response to Aplysia Abyssovirus 1 in nervous system and gill.Developmental and comparative immunology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jin LengDepartment of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA.
Daniel R Goldstein
Yale University · US

Funding

Mechanisms to augment primary immunity in agingR01AG028082 · NIA · YALE UNIVERSITY · PI DENG, JANE C · 2007 to 2023
$6.9M
Aging, Viral Immunity and AtherosclerosisK02AG033049 · NIA · YALE UNIVERSITY · PI GOLDSTEIN, DANIEL ROBERT · 2008 to 2012
$737k
NIA NIH HHS AG028082NIA NIH HHS AG033049NIA NIH HHS K02 AG033049NIA NIH HHS R01 AG028082
6 · The paper itself

Abstract

Older people are more susceptible to a variety of viral infections, including those that induce respiratory disease, resulting in higher morbidity and mortality than younger people. Aging impacts both innate and adaptive arms of the immune system to impair control of viral infections. This review will summarize key findings on how aging impacts immunity to viral infection.

Indexed as

AgingAdaptive ImmunityHumansImmunity, InnateVirus Diseases

Identifiers

PMID20849976
PMCPMC2998572
OpenAlexW2036716735

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.