Evidence map›Paper›PMID 20849685›Full record

Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2010

Prodromal schizophrenia in primary care: a randomised sensitisation study.

Andor E Simon, Sabrina Jegerlehner, Thomas Müller, Katja Cattapan-Ludewig, Peter Frey, Marcus Grossenbacher, Erich Seifritz, Daniel Umbricht

Open access · bronzeAbstract readMulticenter StudyRandomized Controlled Trial
In one paragraph

Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
0.5field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Andor E SimonUniversity Hospital of Psychiatry, University of Bern. andor.simon@bluewin.ch
Sabrina Jegerlehner
Thomas Müller
Katja Cattapan-Ludewig
Peter Frey
Marcus Grossenbacher
Erich Seifritz
Daniel Umbricht
University Hospital of Zurich · CHUniversity of Zurich · CHUniversity of Bern · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGPs are often the first point of contact for patients with prodromal schizophrenia. Early intervention, and therefore early detection, of schizophrenia is pivotal for the further disease course. However, recent studies have revealed that, due to its low prevalence in general practice and its insidious features, prodromal schizophrenia often remains unnoticed.

aimTo test whether a repeated sensitisation method using clinical vignettes can improve diagnostic knowledge of GPs. DESIGN OF STUDY: Postal survey using anonymous questionnaires. Repeated sensitisation model using clinical vignettes.

settingGPs in three distinct regions in Switzerland covering a general population of 1.43 million.

methodThe study was conducted between September 2008 and October 2009. Questionnaires were sent to 1138 GPs at baseline, and at 6 and 12 months. After randomisation, 591 GPs were sensitised at 1, 3, and 5 months, while no sensitisation was carried out in the remaining 547 GPs.

resultsThe overall response rate was 66% (750 GPs). Sensitised GPs demonstrated a highly significant increase in diagnostic knowledge at 6 and at 12 months when compared to their own baseline knowledge scores and also to non-sensitised GPs (P<0.001). In particular, awareness of insidious features, such as functional decline and social withdrawal as signs of prodromal schizophrenia, accounted for this effect.

conclusionTheoretical knowledge of prodromal schizophrenia among GPs can successfully be increased by repeated sensitisation models using clinical vignettes.

Indexed as

Analysis of VarianceClinical CompetenceEarly DiagnosisGeneral PracticeHumansPrognosisSchizophreniaSurveys and QuestionnairesSwitzerland

Identifiers

PMID20849685
PMCPMC2930245
OpenAlexW2163318273

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.