ArticleBMC genomics2010
Homoeolog-specific transcriptional bias in allopolyploid wheat.
Article in BMC genomics, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 76 papers, 1 of them a synthesis that pooled it.
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Who cites it
76 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Impact of genome duplication on secondary metabolite composition in non-cultivated species: a systematic meta-analysis.Annals of botany · 2020Pooled it
- Diploid- and tetraploid wall barley exhibit alternative molecular responses but comparable reproductive performance in response to different ambient temperature regimes.The Plant journal : for cell and molecular biology · 2026Article
- Genome-Wide Characterization and Light-Responsive Expression Patterns of B-Box Transcription Factors inPlants (Basel, Switzerland) · 2026Article
- Genetic diversity and population structure of a core collection of Mediterranean durum wheat accessions using DArTseq markers.BMC genomics · 2025Article
- Regulation of nucleolar dominance through allopolyploidization of hexaploid wheat.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2025Article
- Epigenetic insights into the domestication of tetraploid peanut.Plant physiology · 2025Article
- Recent allopolyploidization and transcriptomic asymmetry in the mangrove shrub Acanthus tetraploideus.BMC genomics · 2025Article
- Improving genomic selection in hexaploid wheat with sub-genome additive and epistatic models.G3 (Bethesda, Md.) · 2025Article
- Article
- Transcriptomics and Metabolomics Reveal Biosynthetic Pathways and Regulatory Mechanisms of Phenylpropanes in Different Ploidy ofPlants (Basel, Switzerland) · 2024Article
- Functional Characterization of Accessible Chromatin in Common Wheat.International journal of molecular sciences · 2024Article
- Electroacupuncture protective effects after cerebral ischemia are mediated through miR-219a inhibition.Biological research · 2023Article
- Duplicate Genes Contribute to Variability in Abiotic Stress Resistance in Allopolyploid Wheat.Plants (Basel, Switzerland) · 2023Review
- Low impact of polyploidization on the transcriptome of synthetic allohexaploid wheat.BMC genomics · 2023Article
- Global Patterns of Subgenome Evolution in Organelle-Targeted Genes of Six Allotetraploid Angiosperms.Molecular biology and evolution · 2022Article
- Over-expression of TaDWF4 increases wheat productivity under low and sufficient nitrogen through enhanced carbon assimilation.Communications biology · 2022Article
- Meta-analysis reveals consensus genomic regions associated with multiple disease resistance in wheat (Molecular breeding : new strategies in plant improvement · 2022Article
- Integrated Analysis of Hi-C and RNA-Seq Reveals the Molecular Mechanism of Autopolyploid Growth Advantages in Pak Choi (Frontiers in plant science · 2022Article
- Spatial and Temporal Transcriptomic Heredity and Asymmetry in an Artificially Constructed Allotetraploid Wheat (AADD).Frontiers in plant science · 2022Article
- Strategies and Bottlenecks in Hexaploid Wheat to Mobilize Soil Iron to Grains.Frontiers in plant science · 2022Review
16 more citing papers are in PubMed but not listed here.
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInteraction between parental genomes is accompanied by global changes in gene expression which, eventually, contributes to growth vigor and the broader phenotypic diversity of allopolyploid species. In order to gain a better understanding of the effects of allopolyploidization on the regulation of diverged gene networks, we performed a genome-wide analysis of homoeolog-specific gene expression in re-synthesized allohexaploid wheat created by the hybridization of a tetraploid derivative of hexaploid wheat with the diploid ancestor of the wheat D genome Ae. tauschii.
resultsAffymetrix wheat genome arrays were used for both the discovery of divergent homoeolog-specific mutations and analysis of homoeolog-specific gene expression in re-synthesized allohexaploid wheat. More than 34,000 detectable parent-specific features (PSF) distributed across the wheat genome were used to assess AB genome (could not differentiate A and B genome contributions) and D genome parental expression in the allopolyploid transcriptome. In re-synthesized polyploid 81% of PSFs detected mid-parent levels of gene expression, and only 19% of PSFs showed the evidence of non-additive expression. Non-additive expression in both AB and D genomes was strongly biased toward up-regulation of parental type of gene expression with only 6% and 11% of genes, respectively, being down-regulated. Of all the non-additive gene expression, 84% can be explained by differences in the parental genotypes used to make the allopolyploid. Homoeolog-specific co-regulation of several functional gene categories was found, particularly genes involved in photosynthesis and protein biosynthesis in wheat.
conclusionsHere, we have demonstrated that the establishment of interactions between the diverged regulatory networks in allopolyploids is accompanied by massive homoeolog-specific up- and down-regulation of gene expression. This study provides insights into interactions between homoeologous genomes and their role in growth vigor, development, and fertility of allopolyploid species.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.