ArticleAnalytical chemistry2010
Near infrared luminescent oxygen nanosensors with nanoparticle matrix tailored sensitivity.
Article in Analytical chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
29 citing papers in PubMed, 99 citations in OpenAlex.
- A fluorous-phase oxygen optical nanosensor for mitigating redox-active microbial metabolite interference.The Analyst · 2026Article
- Luminescent core-isolated solvent-free liquids as a soft material platform for optical gas sensing.Chemical science · 2026Article
- Shining New Light on Biological Systems: Luminescent Transition Metal Complexes for Bioimaging and Biosensing Applications.Chemical reviews · 2024Review
- Nanoparticles for Interrogation of Cell Signaling.Annual review of analytical chemistry (Palo Alto, Calif.) · 2023Review
- Nanocomposite Hydrogels as Functional Extracellular Matrices.Gels (Basel, Switzerland) · 2023Review
- NIR Luminescent Oxygen-Sensing Nanoparticles for Continuous Glucose and Lactate Monitoring.Biosensors · 2023Article
- Review
- Ru(ii)/BODIPY core co-encapsulated ratiometric nanotools for intracellular ORSC chemical biology · 2021Article
- Review: Nanomaterials for Reactive Oxygen Species Detection and Monitoring in Biological Environments.Frontiers in chemistry · 2021Review
- Article
- Monitoring Oxygen Levels within Large, Tissue-Engineered Constructs Using Porphyin-Hydrogel Microparticles.ACS biomaterials science & engineering · 2019Article
- Nanoparticle-based fluoroionophore for analysis of potassium ion dynamics in 3D tissue models andAdvanced functional materials · 2018Article
- Imaging the pharmacology of nanomaterials by intravital microscopy: Toward understanding their biological behavior.Advanced drug delivery reviews · 2017Review
- Luminescent sensing and imaging of oxygen: fierce competition to the Clark electrode.BioEssays : news and reviews in molecular, cellular and developmental biology · 2015Review
- Soft fluorescent nanomaterials for biological and biomedical imaging.Chemical Society reviews · 2015Review
- Ratiometric Molecular Probes Based on Dual Emission of a Blue Fluorescent Coumarin and a Red Phosphorescent Cationic Iridium(III) Complex for Intracellular Oxygen Sensing.Sensors (Basel, Switzerland) · 2015Article
- Emerging applications of porphyrins in photomedicine.Frontiers in physics · 2015Article
- Imaging oxygen in neural cell and tissue models by means of anionic cell-permeable phosphorescent nanoparticles.Cellular and molecular life sciences : CMLS · 2015Article
- Oxygen and seizure dynamics: I. Experiments.Journal of neurophysiology · 2014Article
- Two-photon antenna-core oxygen probe with enhanced performance.Analytical chemistry · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
Abstract
The development of sensors for noninvasive determination of oxygen levels in live cells and tissues is critical for the understanding of cellular functions, as well as for monitoring the status of disease, such as cancer, and for predicting the efficacy of therapy. We describe such nontoxic, targeted, and ratiometric 30 nm oxygen nanosensors made of polyacrylamide hydrogel, near-infrared (NIR) luminescent dyes, and surface-conjugated tumor-specific peptides. They enabled noninvasive real-time monitoring of oxygen levels in live cancer cells under normal and hypoxic conditions. The required sensitivity, brightness, selectivity, and stability were achieved by tailoring the interaction between the nanomatrix and indicator dyes. The developed nanosensors may become useful for in vivo oxygen measurements.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.