Hindering of proteinopathy-induced neurodegeneration as a new mechanism of action for neuroprotectors and cognition enhancing compounds.

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

10 citing papers in PubMed.

1. The Effect of Ionizing Radiation on Cognitive Functions in Mouse Models of Alzheimer's Disease.Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections · 2020
   Article
2. Novel Sites of Neuroprotective Action of Dimebon (Latrepirdine).Molecular neurobiology · 2015
   Review
3. Gamma-carboline inhibits neurodegenerative processes in a transgenic model of amyotrophic lateral sclerosis.Doklady. Biochemistry and biophysics · 2015
   Article
4. Latrepirdine: molecular mechanisms underlying potential therapeutic roles in Alzheimer's and other neurodegenerative diseases.Translational psychiatry · 2013
   Review
5. Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.Journal of Alzheimer's disease : JAD · 2012
   Article
6. Dimebon does not ameliorate pathological changes caused by expression of truncated (1-120) human alpha-synuclein in dopaminergic neurons of transgenic mice.Neuro-degenerative diseases · 2011
   Article
7. Testing the amyloid hypothesis of Alzheimer's disease in vivo.The Lancet. Neurology · 2010
   Article
8. Dimebon activates autophagosome components in human neuroblastoma SH-SY5Y cells.Doklady. Biochemistry and biophysics
   Article
9. Gamma-Carbolines Derivatives As Promising Agents for the Development of Pathogenic Therapy for Proteinopathy.Acta naturae
   Article
10. FUS gene mutations associated with familiar forms of amyotrophic lateral sclerosis affect cellular localization and aggregation properties of the encoded protein.Doklady. Biochemistry and biophysics
    Article

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

Authors and funding

6 authors.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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