ArticleHead & neck2011
Case-matching analysis of head and neck squamous cell carcinoma in racial and ethnic minorities in the United States--possible role for human papillomavirus in survival disparities.
Article in Head & neck, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 64 citations in OpenAlex.
- Oropharyngeal Carcinoma with a Special Focus on HPV-Related Squamous Cell Carcinoma.Annual review of pathology · 2023Review
- Matched-pair analysis of the impact of low-dose postoperative radiotherapy on prognosis in patients with advanced hypopharyngeal squamous cell carcinoma without positive surgical margins and extracapsular extension.Frontiers in oncology · 2023Article
- Disease-Specific Health Disparities: A Targeted Review Focusing on Race and Ethnicity.Healthcare (Basel, Switzerland) · 2022Review
- Disparities and guideline adherence for HPV testing among patients with oropharyngeal squamous cell carcinoma, NCDB, and SEER.Head & neck · 2021Article
- Socioeconomic Status Drives Racial Disparities in HPV-negative Head and Neck Cancer Outcomes.The Laryngoscope · 2021Article
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- Immunometabolic Alterations by HPV Infection: New Dimensions to Head and Neck Cancer Disparity.Journal of the National Cancer Institute · 2019Review
- Matched-pair analysis of patients with advanced hypopharyngeal cancer: surgery versus concomitant chemoradiotherapy.International journal of clinical oncology · 2017Article
- Differences in the Prevalence of Human Papillomavirus (HPV) in Head and Neck Squamous Cell Cancers by Sex, Race, Anatomic Tumor Site, and HPV Detection Method.JAMA oncology · 2017Article
- Socioeconomic and Other Demographic Disparities Predicting Survival among Head and Neck Cancer Patients.PloS one · 2016Observational
- Racial Disparity Among the Head and Neck Cancer Population.Journal of cancer education : the official journal of the American Association for Cancer Education · 2015Review
- The clinical impact of HPV tumor status upon head and neck squamous cell carcinomas.Oral oncology · 2014Review
- Racial and Ethnic Disparities in Salivary Gland Cancer Survival.JAMA otolaryngology-- head & neck surgery · 2014Article
- Improved survival with HPV among African Americans with oropharyngeal cancer.Clinical cancer research : an official journal of the American Association for Cancer Research · 2013Article
- Neighborhood deprivation and clinical outcomes among head and neck cancer patients.Health & place · 2012Article
- Virology and molecular pathogenesis of HPV (human papillomavirus)-associated oropharyngeal squamous cell carcinoma.The Biochemical journal · 2012Review
- Decreased overall survival in black patients with HPV-associated oropharyngeal cancer.American journal of otolaryngologyArticle
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Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
Abstract
backgroundSeveral studies have documented disparities in head and neck cancer outcomes for black patients in the United States. Recent studies have found that differences in oropharyngeal tumor human papillomavirus (HPV) status may be a cause of this disparity.
methodsIn all, 76,817 cases of head and neck squamous cell carcinoma (HNSCC) recorded in the National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) program were analyzed. Racial/ethnic groups were studied, for disease-specific survival in both case-matched and nonmatched cohorts. Calculation of expected disparity magnitudes based on HPV status was performed using data reported in the literature.
resultsA disease-specific survival disparity was demonstrated for Hispanic patients. However, case matching eliminated this disparity. Conversely, the disparity for black patients persisted in matched cohorts. The oropharyngeal subsite was found to be the dominant contributor to this disparity.
conclusionsThe survival disparity for Hispanic patients in SEER with HNSCC is explained by differences in presentation and treatment. Also, HPV tumor status is likely a key determinant of the disparity for black patients.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.