ArticleVirology journal2010
Echoviruses are a major cause of aseptic meningitis in infants and young children in Kuwait.
Article in Virology journal, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed, 43 citations in OpenAlex.
- An Overview of the Characteristics, Pathogenesis, Epidemiology, and Detection of Human Enterovirus in the Arabian Gulf Region.Viruses · 2024Review
- Molecular characterization of enterovirus detected in cerebrospinal fluid and wastewater samples in Monastir, Tunisia, 2014-2017.Virology journal · 2022Article
- Enteroviral Infections in the First Three Months of Life.Pathogens (Basel, Switzerland) · 2022Review
- Etiology, Clinical Phenotypes, Epidemiological Correlates, Laboratory Biomarkers and Diagnostic Challenges of Pediatric Viral Meningitis: Descriptive Review.Frontiers in pediatrics · 2022Review
- Epidemiological characteristics and climatic variability of viral meningitis in Kazakhstan, 2014-2019.Frontiers in public health · 2022Article
- Molecular epidemiology of enteroviruses and predominance of echovirus 30 in an Iranian population with aseptic meningitis.Journal of neurovirology · 2021Article
- Viral meningitis: an overview.Archives of virology · 2021Review
- Epidemiology Profile of Viral Meningitis Infections Among Patients in Qatar (2015-2018).Frontiers in medicine · 2021Article
- High rate of human enteroviruses among clinically suspected meningitis cases at selected Hospitals in Addis Ababa, Ethiopia.PloS one · 2021Article
- Comparison of clinical and laboratory characteristics during two major paediatric meningitis outbreaks of echovirus 30 and other non-polio enteroviruses in Germany in 2008 and 2013.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2017Article
- Human enteroviruses in cerebrospinal fluid of children with suspected aseptic meningitis: A study in northern Iran.Caspian journal of internal medicine · 2017Article
- Article
- Molecular identification of human enteroviruses associated with aseptic meningitis in Yunnan province, Southwest China.SpringerPlus · 2016Article
- Study of the Frequency of Herpesvirus Infections Among Patients Suspected Aseptic Meningitis in the West of Iran.Jundishapur journal of microbiology · 2015Article
- Viral diseases of the central nervous system.Current opinion in virology · 2015Review
- Article
- Enterovirus infections of the central nervous system.Virology · 2011Review
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe etiologic agents of aseptic meningitis (AM) often include human enteroviruses. The role of enteroviruses causing AM in young children was investigated during a 3-year period in Kuwait.
resultsEnteroviral RNA was detected in cerebrospinal fluid (CSF) by reverse transcription-PCR and specific genotypes of enteroviruses were identified by direct DNA sequencing of VP4-VP2 region. Enteroviral RNA was detected in 92 of 387 (24%) suspected AM cases and the results were confirmed by hybridization of amplicons with an internal, enterovirus-specific probe. The CSF samples from 75 of 281 (27%) children < 2 years old but only from 3 of 38 (8%) 4-12 year-old children were positive for enteroviral RNA (p = 0.011). Majority of infections in children < 2 years old (49 of 75, 65%) were due to three echoviruses; echovirus type 9 (E9), E11 and E30. Only three other enteroviruses, namely coxsackievirus type B4, coxsackievirus type B5 and enterovirus 71 were detected among AM cases in Kuwait.
conclusionsOur data show that three types of echoviruses (E9, E11 and E30) are associated with the majority of AM cases in Kuwait. To the best of our knowledge, this is the first report to characterize different enterovirus genotypes associated with AM in the Arabian Gulf region.
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