ReviewThe Journal of infectious diseases2010
Clinical management of acute HIV infection: best practice remains unknown.
Review in The Journal of infectious diseases, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Pooled it
- Short-course antiretroviral therapy in primary HIV infection.The New England journal of medicine · 2013Trial
- The setpoint study (ACTG A5217): effect of immediate versus deferred antiretroviral therapy on virologic set point in recently HIV-1-infected individuals.The Journal of infectious diseases · 2012Trial
- No treatment versus 24 or 60 weeks of antiretroviral treatment during primary HIV infection: the randomized Primo-SHM trial.PLoS medicine · 2012Trial
- High HIV Incidence Among HIV-Infected But Undetected Individuals Seeking HIV Voluntary Counselling and Testing Services in the Greater Masaka Region in Uganda.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Cohort Profile: The Zurich Primary HIV Infection Study.Microorganisms · 2024Article
- Arsenic trioxide-induced apoptosis contributes to suppression of viral reservoir in SIV-infected rhesus macaques.Microbiology spectrum · 2023Article
- A study on the dynamics of temporary HIV treatment to assess the controversial outcomes of clinical trials: An in-silico approach.PloS one · 2018Article
- Acute HIV infection presenting as hemophagocytic syndrome with an unusual serological and virological response to ART.BMC infectious diseases · 2016Article
- Participation in HIV cure-related research: a scoping review of the proxy literature and implications for future research.Journal of virus eradication · 2015Article
- Poor performance of the determine HIV-1/2 Ag/Ab combo fourth-generation rapid test for detection of acute infections in a National Household Survey in Swaziland.Journal of clinical microbiology · 2014Article
- Predictors of virologic response in persons who start antiretroviral therapy during recent HIV infection.AIDS (London, England) · 2014Observational
- Antiretroviral therapy initiated during acute HIV infection fails to prevent persistent T-cell activation.Journal of acquired immune deficiency syndromes (1999) · 2013Article
- Article
- Central nervous system viral invasion and inflammation during acute HIV infection.The Journal of infectious diseases · 2012Article
- Detection of acute HIV infection: a field evaluation of the determine® HIV-1/2 Ag/Ab combo test.The Journal of infectious diseases · 2012Article
- Impact of multi-targeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection.PloS one · 2012Article
- Prolonged control of replication-competent dual- tropic human immunodeficiency virus-1 following cessation of highly active antiretroviral therapy.Retrovirology · 2011Article
- The role of acute and early HIV infection in the spread of HIV and implications for transmission prevention strategies in Lilongwe, Malawi: a modelling study.Lancet (London, England) · 2011Article
- Acute HIV-1 Infection.The New England journal of medicine · 2011Review
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Best practice for the clinical management of acute human immunodeficiency virus (HIV) infection remains unknown. Although some data suggest possible immunologic, virologic, or clinical benefit of early treatment, other studies show no difference in these outcomes over time, after early treatment is discontinued. The literature on acute HIV infection is predominantly small nonrandomized studies, which further limits interpretation. As a result, the physician is left to grapple with these uncertainties while making clinical decisions for patients with acute HIV infection. Here we review the literature, focusing on the potential advantages and disadvantages of treating acute HIV infection outlined in treatment guidelines, and summarize the presentations on clinical management of acute HIV infection from the 2009 Acute HIV Infection Meeting in Boston, Massachusetts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.