Evidence map›Paper›PMID 20845919›Full record

ArticleAnalytical chemistry2010

Transcutaneous glucose sensing by surface-enhanced spatially offset Raman spectroscopy in a rat model.

Jonathan M Yuen, Nilam C Shah, Joseph T Walsh, Matthew R Glucksberg, Richard P Van Duyne

Abstract read
In one paragraph

Article in Analytical chemistry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed.

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  11. Plasmonic Nanoparticles: Advanced Researches (II).Advances in experimental medicine and biology · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jonathan M Yuen
Nilam C Shah
Joseph T Walsh
Matthew R Glucksberg
Richard P Van Duyne

Funding

Surface-Enhanced Raman Glucose SensorR56DK078691 · NIDDK · NORTHWESTERN UNIVERSITY · PI VAN DUYNE, RICHARD PALMER · 2008 to 2009
$528k
NIDDK NIH HHS 5R56DK078691-02NIDDK NIH HHS R56 DK078691
6 · The paper itself

Abstract

This letter presents the first quantitative, in vivo, transcutaneous glucose measurements using surface enhanced Raman spectroscopy (SERS). Silver film over nanosphere (AgFON) surfaces were functionalized with a mixed self-assembled monolayer (SAM) and implanted subcutaneously in a Sprague-Dawley rat. The glucose concentration was monitored in the interstitial fluid. SER spectra were collected from the sensor chip through the skin using spatially offset Raman spectroscopy (SORS). The combination of SERS and SORS is a powerful new approach to the challenging problem of in vivo metabolite and drug sensing.

Indexed as

AnimalsExtracellular FluidGlucoseMaleNanostructuresRatsRats, Sprague-DawleySkinSpectrum Analysis, RamanSurface PropertiesGlucose

Identifiers

PMID20845919
PMCPMC3031996

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.