ArticleAngewandte Chemie (International ed. in English)2010
cat-ELCCA: a robust method to monitor the fatty acid acyltransferase activity of ghrelin O-acyltransferase (GOAT).
Article in Angewandte Chemie (International ed. in English), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- RiPCA: An Assay for the Detection of RNA-Protein Interactions in Live Cells.Current protocols · 2022Article
- Review
- Ghrelin octanoylation by ghrelinOpen biology · 2021Review
- A Not-So-Ancient Grease History: Click Chemistry and Protein Lipid Modifications.Chemical reviews · 2021Review
- Article
- Recent progress in the discovery of ghrelinRSC medicinal chemistry · 2020Review
- An overview of ghrelinExpert opinion on therapeutic patents · 2020Review
- Acylation-coupled lipophilic induction of polarisation (Acyl-cLIP): a universal assay for lipid transferase and hydrolase enzymes.Chemical science · 2019Article
- A click chemistry assay to identify natural product ligands for pre-microRNAs.Methods in enzymology · 2019Article
- cat-ELCCA: catalyzing drug discovery through click chemistry.Chemical communications (Cambridge, England) · 2018Article
- Expansion of cat-ELCCA for the Discovery of Small Molecule Inhibitors of the Pre-let-7-Lin28 RNA-Protein Interaction.ACS medicinal chemistry letters · 2018Article
- Development and Implementation of an HTS-Compatible Assay for the Discovery of Selective Small-Molecule Ligands for Pre-microRNAs.SLAS discovery : advancing life sciences R & D · 2018Article
- High-Throughput Chemical Probing of Full-Length Protein-Protein Interactions.ACS combinatorial science · 2017Article
- Microfluidic Mobility Shift Assay for Real-Time Analysis of Peptide N-Palmitoylation.SLAS discovery : advancing life sciences R & D · 2017Article
- Article
- A click chemistry-based microRNA maturation assay optimized for high-throughput screening.Chemical communications (Cambridge, England) · 2016Article
- Click chemistry armed enzyme-linked immunosorbent assay to measure palmitoylation by hedgehog acyltransferase.Analytical biochemistry · 2015Article
- Mechanistic analysis of ghrelin-O-acyltransferase using substrate analogs.Bioorganic chemistry · 2015Article
- Novel Regulator of Acylated Ghrelin, CF801, Reduces Weight Gain, Rebound Feeding after a Fast, and Adiposity in Mice.Frontiers in endocrinology · 2015Article
- Ghrelin O-acyltransferase assays and inhibition.Methods in enzymology · 2012Review
Corrections and comments
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Authors and funding
2 authors.
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Abstract
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.