Evidence map›Paper›PMID 20842218›Full record

ArticleJournal of Cancer2010

Breast cancer heterogeneity: mechanisms, proofs, and implications.

Yi-Hsuan Hsiao, Ming-Chih Chou, Carol Fowler, Jeffrey T Mason, Yan-Gao Man

Abstract read
In one paragraph

Article in Journal of Cancer, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Overexpression of Rho-Associated Coiled-Coil Containing Protein Kinase 2 Is Correlated with Clinical Progression and Poor Prognosis in Breast Cancer.Medical science monitor : international medical journal of experimental and clinical research · 2018
    Article
  15. Article
  16. Mathematical models of breast and ovarian cancers.Wiley interdisciplinary reviews. Systems biology and medicine · 2016
    Review
  17. Article
  18. Review
  19. Decreased expression of SOX17 is associated with tumor progression and poor prognosis in breast cancer.Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine · 2015
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Yi-Hsuan Hsiao1. Institute of Medicine, Chung Shan Medical University, Taiwan.
Ming-Chih Chou
Carol Fowler
Jeffrey T Mason
Yan-Gao Man

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human breast cancer represents a group of highly heterogeneous lesions consisting of about 20 morphologically distinct subtypes with substantially different molecular and/or biochemical signatures, clinical courses, and prognoses. This study analyzed the possible correlation between the morphological presentations of breast cancer and two hypothesized models of carcinogenesis, in order to identify the intrinsic mechanism(s) and clinical implications of breast cancer heterogeneity.

Indexed as

breast cancer heterogeneityclinical implicationhypothesized modelmechanism

Identifiers

PMID20842218
PMCPMC2931354

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.