ReviewNature reviews. Neurology2010
Imaging of acute stroke.
Review in Nature reviews. Neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
61 citing papers in PubMed, 3 syntheses or guidelines pooled it, 147 citations in OpenAlex.
- Pre-thrombectomy prognostic prediction of large-vessel ischemic stroke using machine learning: A systematic review and meta-analysis.Frontiers in neurology · 2022Pooled it
- Lesion loci of impaired affective prosody: A systematic review of evidence from stroke.Brain and cognition · 2021Pooled it
- Diagnostic criteria for vascular cognitive disorders: a VASCOG statement.Alzheimer disease and associated disordersGuideline
- Safety and Efficacy of Intravenous Thrombolysis by Infarct Type in Patients with No Visible Occlusion: A Secondary Analysis of the AcT Trial.Journal of the American Heart Association · 2025Trial
- Choking leading to cardiac arrest and subsequent atypical radiological features of brain damage: A case report.Radiology case reports · 2026Article
- pH-sensitive probes for ischemic stroke: advancing early detection and accurate grading.Frontiers in molecular biosciences · 2026Review
- Review
- Pathophysiological Links Between Stroke and Prediabetes: A Systematic Review.Current issues in molecular biology · 2025Review
- DeepISLES: a clinically validated ischemic stroke segmentation model from the ISLES'22 challenge.Nature communications · 2025Article
- Non-Contrast Computed Tomography-Based Triage and Notification for Large Vessel Occlusion Stroke: A Before and After Study Utilizing Artificial Intelligence on Treatment Times and Outcomes.Journal of clinical medicine · 2025Article
- Comprehensive voxel-wise, tract-based, and network lesion mapping reveals unique architectures of right and left visuospatial neglect.Brain structure & function · 2023Article
- Association Between Duration of Transient Neurological Events and Diffusion-Weighted Brain Lesions.Journal of the American Heart Association · 2023Article
- Case report: Flow changes in routes of collateral circulation in patients with LVO and low NIHSS: a point favor to treat.Frontiers in neurology · 2023Article
- Performance of RAPID noncontrast CT stroke platform in large vessel occlusion and intracranial hemorrhage detection.Frontiers in neurology · 2023Article
- Low-field MRI: Clinical promise and challenges.Journal of magnetic resonance imaging : JMRI · 2023Review
- Artificially-reconstructed brain images with stroke lesions from non-imaging data: modeling in categorized patients based on lesion occurrence and sparsity.Scientific reports · 2022Article
- End-to-End Deep Learning Approach for Perfusion Data: A Proof-of-Concept Study to Classify Core Volume in Stroke CT.Diagnostics (Basel, Switzerland) · 2022Article
- Recent Advances in Nanomaterials for Diagnosis, Treatments, and Neurorestoration in Ischemic Stroke.Frontiers in cellular neuroscience · 2022Review
- A low-cost and shielding-free ultra-low-field brain MRI scanner.Nature communications · 2021Article
- Right and left neglect are not anatomically homologous: A voxel-lesion symptom mapping study.Neuropsychologia · 2021Article
1 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
Brain imaging provides an objective basis for the clinical inferences that direct individual patient management in the acute stroke setting. A brain CT or MRI scan is required for all patients with suspected stroke or transient ischemic attack. Thrombolytic therapy is arguably the most important aspect of acute stroke management; however, most decisions in acute stroke do not relate to this treatment. Stroke imaging must, therefore, provide information beyond the presence or absence of intracranial hemorrhage (ICH) and early evidence of a large infarct. Noncontrast CT and gradient-recalled echo MRI show comparable accuracy in the diagnosis of acute ICH. Diffusion-weighted MRI is more sensitive than noncontrast CT for differentiation of acute ischemic stroke from nonstroke conditions. Combined multimodal parenchymal, perfusion and vascular imaging with CT or MRI has the potential to identify patients with an ischemic penumbra that might be appropriate for acute reperfusion therapies. MRI identifies a broader range of acute and chronic cerebrovascular pathologies than does CT and, hence, could aid decisions about acute intervention, in-hospital management, and secondary prevention. Here, we present an overview of the diagnostic information that clinicians might gain from CT and MRI in the setting of acute stroke, along with the advantages and disadvantages of these techniques.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.