ReviewNature reviews. Neurology2010
Imaging in the surgical treatment of epilepsy.
Review in Nature reviews. Neurology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
79 citing papers in PubMed, 213 citations in OpenAlex.
- Functional magnetic resonance imaging based on Chinese tasks to protect language function in epileptics.Brain and behavior · 2021Trial
- Neural correlates of short-term memory reorganization in humans with hippocampal damage.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2013Trial
- Volume-inflation registration (INFREG) for morphometric analysis of human focal cortical dysplasia type II.iScience · 2026Article
- Etiologies of patients with adult-onset epilepsy over the past 25 years: a retrospective study in China.BMC neurology · 2025Article
- Enhanced Detection of Epileptogenic Zone Using Prisma 3T MRI in Patients with MRI-negative Focal Epilepsy.World neurosurgery · 2025Article
- MRI Interpretation Errors in Adult Patients with Medically Refractory Epilepsy.AJNR. American journal of neuroradiology · 2025Observational
- Assessing Functional Connectivity Dynamics During Cognitive Tasks Involving the Dorsal Stream.Entropy (Basel, Switzerland) · 2025Article
- Automated Detection of Aberrant Episodes in Epileptic Conditions: Leveraging EEG and Machine Learning Algorithms.Bioengineering (Basel, Switzerland) · 2025Article
- Hyperpolarized [1-Brain communications · 2025Article
- Correlation of magnetic resonance spectroscopy and magnetic resonance imaging with findings of electroencephalography in patients with temporal lobe epilepsy.Journal of medical radiation sciences · 2024Article
- Novel Surgical Approaches in Childhood Epilepsy: Laser, Brain Stimulation, and Focused Ultrasound.Advances and technical standards in neurosurgery · 2024Article
- Clinical characteristics of MRI-negative temporal lobe epilepsy.Acta neurologica Belgica · 2023Article
- State of the Art and Challenges in Epilepsy-A Narrative Review.Journal of personalized medicine · 2023Review
- Validation of a novel path planner for stereotactic neurosurgical interventions-A retrospective clinical study.The international journal of medical robotics + computer assisted surgery : MRCAS · 2022Article
- MRI-Guided Electrode Implantation for Chronic Intracerebral Recordings in a Rat Model of Post-Traumatic Epilepsy-Challenges and Gains.Biomedicines · 2022Article
- The role of hybrid FDG-PET/MRI on decision-making in presurgical evaluation of drug-resistant epilepsy.BMC neurology · 2021Article
- UltraHigh Field MR Imaging in Epilepsy.Magnetic resonance imaging clinics of North America · 2021Review
- Contribution of Ictal Source Imaging for Localizing Seizure Onset Zone in Patients With Focal Epilepsy.Neurology · 2021Article
- Mapping Epileptic Networks Using Simultaneous Intracranial EEG-fMRI.Frontiers in neurology · 2021Article
- DUSP4 appears to be a highly localized endogenous inhibitor of epileptic signaling in human neocortex.Neurobiology of disease · 2020Article
19 more citing papers are in PubMed but not listed here.
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Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Medically refractory focal epilepsy is potentially curable by surgery. This Review considers the application of recent advances in structural and functional brain imaging to increase the number of patients with epilepsy who are treated surgically, and to reduce the risk of complications arising from such intervention. Current optimal MRI of brain structure can identify previously undetectable lesions, with voxel-based and quantitative analyses further increasing the diagnostic yield. If MRI proves unremarkable, PET (with (18)F-fluorodeoxyglucose) and single-photon emission CT of ictal-interictal cerebral blood flow might identify the brain region that contains the epileptic focus. Magnetoencephalography plus simultaneous EEG and functional MRI can map the location of interictal epileptic discharges, thereby facilitating placement of intracranial recording electrodes to define the site of seizure onset. Functional MRI can also lateralize language and localize primary motor, somatosensory and language areas, and shows promise for predicting the effects of temporal lobe resection on memory. Tractography can visualize the main cerebral white matter tracts, thereby predicting and reducing surgery risk. Currently, displays of the optic radiation and pyramidal tracts are the most relevant for epilepsy surgery. Reliable integration of structural and functional data into surgical image-guidance systems is being pursued, and promises safer neurosurgery for epilepsy in the future.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.