Evidence map›Paper›PMID 20840795›Full record

ArticleBMC family practice2010

Qualitative insights into general practitioners views on polypharmacy.

Sibyl Anthierens, Anneleen Tansens, Mirko Petrovic, Thierry Christiaens

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in BMC family practice, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03903484 (A Collaborative Intervention for Streamlining Medication Appropriateness and Deprescribing Within Integrated Health-Care Teams), which is not on this map. Cited by 71 papers, 8 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
71citing papers in PubMed, 8 pooled it
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03903484 nacompletednot on this mapstarted 2019, after this paper: background citation

A Collaborative Intervention for Streamlining Medication Appropriateness and Deprescribing Within Integrated Health-Care Teams

TypeinterventionalSponsorNova Scotia Health AuthorityRan2019 to 2022Enrolled7ConditionsInappropriate Prescribing, Primary Health Care, PolypharmacyArmsDeprescribing toolbox and intervention
3 · Its place in the literature

Who cites it

71 citing papers in PubMed, 8 syntheses or guidelines pooled it, 147 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Deprescribing benzodiazepine receptor agonists: Evidence-based clinical practice guideline.Canadian family physician Medecin de famille canadien · 2018
    Guideline
  5. Guideline
  6. Deprescribing proton pump inhibitors: Evidence-based clinical practice guideline.Canadian family physician Medecin de famille canadien · 2017
    Guideline
  7. Pooled it
  8. Pooled it
  9. Trial
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  14. Article
  15. Article
  16. Prescribing patterns and medication costs in patients on maintenance haemodialysis and peritoneal dialysis.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Article

11 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 3 countries.

Sibyl AnthierensVaccine & Infectious Disease Institute & Centre for Primary Care, University of Antwerp, Belgium. sibyl.anthierens@ua.ac.be
Anneleen Tansens
Mirko Petrovic
Thierry Christiaens
Ghent University Hospital · BEInstitute of Pharmacology · CZUniversity of Antwerp · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPolypharmacy is common among older people. The purpose of this study is to describe GPs' views and beliefs on polypharmacy in order to identify the role of the GP in relation to improving prescribing behaviour. The awareness of these often established beliefs is key for understanding behaviour and promoting change which can guide action towards more rational prescribing.

methodsA qualitative descriptive methodology was used with semi-structured interviews. Interviews were conducted with 65 GPs from the region of Aalst, a district of a mixed urban and rural population in Belgium. The aim of the study was to describe the GPs' perspectives on polypharmacy in primary care.

resultsGPs acknowledge that polypharmacy is a problem in their older patient population, especially because of the risk of adverse drug reactions, interactions and lowered adherence. GPs mention that difficulties in keeping an overview of the exact medication intake is an important problem caused by polypharmacy. The patients' strong belief in their medication and self-medication are seen as important barriers in reducing the number of drugs taken. Next to these patient related factors, there are some factors related to the prescriber, such as the lack of regular evaluation of the medication schedule by GPs and the involvement of several prescribers, especially in a hospital setting. According to the respondents, prevention and evidence based medicine guidelines often induce polypharmacy.

conclusionsGPs point out that polypharmacy is an important problem in their older patient population. They see an important role for themselves in optimizing drug regimens for their patients. However, they do not have a readymade solution for polypharmacy. The limited set of options for addressing polypharmacy leave GPs feeling powerless to tackle the problem. There is a need for simple GP friendly tools and access to pharmacotherapeutic advice. Future research in this area and interventions seeking to improve prescribing for the elderly will have to focus on practical tools and take into account the GPs' sense of helplessness.

Indexed as

Attitude of Health PersonnelPhysicians, FamilyPolypharmacyAdultBelgiumFemaleHealth Services ResearchHumansInterviews as TopicMaleMiddle Aged

Identifiers

PMID20840795
PMCPMC2945967
OpenAlexW2156466376

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.