Evidence map›Paper›PMID 20840773›Full record

ArticleCritical care (London, England)2010

International recommendations for glucose control in adult non diabetic critically ill patients.

Carole Ichai, Jean-Charles Preiser, Société Française d'Anesthésie-Réanimation, Société de Réanimation de langue Française, Experts group

Abstract readComparative Study
In one paragraph

Article in Critical care (London, England), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  14. Updates in Glycemic Management in the Hospital.Current diabetes reports · 2019
    Review
  15. Glucose control in the ICU.Current opinion in anaesthesiology · 2019
    Review
  16. Article
  17. Review
  18. Review
  19. Glucose Control in the ICU: A Continuing Story.Journal of diabetes science and technology · 2016
    Review
  20. Glycaemic control in intensive care: Everything in moderation.Journal of the Intensive Care Society · 2016
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Carole IchaiMedical and Surgical Intensive Care Unit, Saint-Roch Hospital, University of Medicine of Nice, 06000 Nice, France. ichai@unice.fr
Jean-Charles Preiser
Société Française d'Anesthésie-Réanimation
Société de Réanimation de langue Française
Experts group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionThe purpose of this research is to provide recommendations for the management of glycemic control in critically ill patients.

methodsTwenty-one experts issued recommendations related to one of the five pre-defined categories (glucose target, hypoglycemia, carbohydrate intake, monitoring of glycemia, algorithms and protocols), that were scored on a scale to obtain a strong or weak agreement. The GRADE (Grade of Recommendation, Assessment, Development and Evaluation) system was used, with a strong recommendation indicating a clear advantage for an intervention and a weak recommendation indicating that the balance between desirable and undesirable effects of an intervention is not clearly defined.

resultsA glucose target of less than 10 mmol/L is strongly suggested, using intravenous insulin following a standard protocol, when spontaneous food intake is not possible. Definition of the severe hypoglycemia threshold of 2.2 mmol/L is recommended, regardless of the clinical signs. A general, unique amount of glucose (enteral/parenteral) to administer for any patient cannot be suggested. Glucose measurements should be performed on arterial rather than venous or capillary samples, using central lab or blood gas analysers rather than point-of-care glucose readers.

conclusionsThirty recommendations were obtained with a strong (21) and a weak (9) agreement. Among them, only 15 were graded with a high level of quality of evidence, underlying the necessity to continue clinical studies in order to improve the risk-to-benefit ratio of glucose control.

Indexed as

Health Planning GuidelinesAdultAge FactorsBlood GlucoseCritical CareCritical IllnessGlucoseGlycemic IndexHumansInsulinInternationalityBlood GlucoseGlucoseInsulin

Identifiers

PMID20840773
PMCPMC3219261

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.