Evidence map›Paper›PMID 20840764›Full record

ArticleTheoretical biology & medical modelling2010

Pathological axes of wound repair: gastrulation revisited.

Maria-Angeles Aller, Jose-Ignacio Arias, Jaime Arias

Open access · hybridAbstract read
In one paragraph

Article in Theoretical biology & medical modelling, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Carcinogenesis: the cancer cell-mast cell connection.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2019
    Review
  5. Review
  6. The gestational power of mast cells in the injured tissue.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2018
    Review
  7. Embrionary way to create a fatty liver in portal hypertension.World journal of gastrointestinal pathophysiology · 2017
    Review
  8. Article
  9. Wound healing reaction: A switch from gestation to senescence.World journal of experimental medicine · 2014
    Review
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Maria-Angeles AllerSurgery I Department, School of Medicine, Complutense University of Madrid, Madrid, Spain.
Jose-Ignacio Arias
Jaime Arias
Hospital Monte Naranco · ESUniversidad Complutense de Madrid · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-traumatic inflammation is formed by molecular and cellular complex mechanisms whose final goal seems to be injured tissue regeneration.In the skin -an exterior organ of the body- mechanical or thermal injury induces the expression of different inflammatory phenotypes that resemble similar phenotypes expressed during embryo development. Particularly, molecular and cellular mechanisms involved in gastrulation return. This is a developmental phase that delineates the three embryonic germ layers: ectoderm, endoderm and mesoderm. Consequently, in the post-natal wounded skin, primitive functions related with the embryonic mesoderm, i.e. amniotic and yolk sac-derived, are expressed. Neurogenesis and hematogenesis stand out among the primitive function mechanisms involved.Interestingly, in these phases of the inflammatory response, whose molecular and cellular mechanisms are considered as traces of the early phases of the embryonic development, the mast cell, a cell that is supposedly inflammatory, plays a key role.The correlation that can be established between the embryonic and the inflammatory events suggests that the results obtained from the research regarding both great fields of knowledge must be interchangeable to obtain the maximum advantage.

Indexed as

AnimalsBlood VesselsGastrulaGastrulationHumansInflammationMast CellsMesodermPhenotypeWound Healing

Identifiers

PMID20840764
PMCPMC2945962
OpenAlexW2133492523

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.