Evidence map›Paper›PMID 20839332›Full record

ReviewCytometry. Part B, Clinical cytometry2010

Monoclonal B cell lymphocytosis: clinical and population perspectives.

Neil E Caporaso, Gerald E Marti, Ola Landgren, Elizabeth Azzato, J Brice Weinberg, Lynn Goldin, Tait Shanafelt

Open access · bronzeAbstract readReview
In one paragraph

Review in Cytometry. Part B, Clinical cytometry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 1 country.

Neil E CaporasoGenetic Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, Maryland 20892, USA. caporaso@nih.gov
Gerald E Marti
Ola Landgren
Elizabeth Azzato
J Brice Weinberg
Lynn Goldin
Tait Shanafelt
National Cancer Institute · USCenter for Biologics Evaluation and Research · USCenter for Cancer Research · USDuke Medical Center · USMayo Clinic · US

Funding

Family Studies ZIACP004410 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI SAVAGE, SHARON A. · 2009 to 2025
$56.1M
Genetic EpidemiologyZIACP005803 · NCI · DIVISION OF CANCER EPIDEMIOLOGY AND GENETICS · PI GOLDSTEIN, ALISA · 2009 to 2025
$24.8M
Molecular and clinical profilingZIABC011352 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LANDGREN, OLA · 2010 to 2014
$4.4M
Population based studiesZIABC011205 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI LANDGREN, OLA · 2009 to 2014
$858k
Intramural NIH HHS ZIA BC011205Intramural NIH HHS ZIA BC011352Intramural NIH HHS ZIA CP004410Intramural NIH HHS ZIA CP005803
6 · The paper itself

Abstract

Monoclonal B Cell Lymphocytosis (MBL) refers to clones of CLL-like cells that exhibit CLL characteristics that fall short of the numbers required for CLL diagnosis. Data from large CLL kindreds document increased prevalence of MBL suggesting a genetic contribution to its etiology. The molecular features that favor progression of MBL to CLL are poorly understood but an elevated B-cell count is a risk factor for progression. An important consideration when evaluating volunteers from CLL families who are willing to donate bone marrow is that MBL be ruled out since the MBL donor clone could result in a second CLL in the recipient. Further studies of MBL are needed to identify the molecular features and how they evolve during progression.

Indexed as

B-LymphocytesBone Marrow TransplantationClone CellsDisease ProgressionHumansLeukemia, Lymphocytic, Chronic, B-CellLymphocyte CountLymphocytosisRisk FactorsTissue Donors

Identifiers

PMID20839332
PMCPMC7282703
OpenAlexW2031873146

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.