SynthesisCytometry. Part B, Clinical cytometry2010
Prevalence of monoclonal B-cell lymphocytosis: a systematic review.
Synthesis in Cytometry. Part B, Clinical cytometry, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed.
- Abnormalities by Multicolor Flow Cytometry for Detection of Minimal Residual Disease in Recipients of Allo-HSCT Originating from Donors: A Cohort StudyTurkish journal of haematology : official journal of Turkish Society of Haematology · 2023Article
- Minimal/Measurable Disease Analysis in Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma by Flow Cytometry.Current protocols · 2022Article
- 14-Color single tube for flow cytometric characterization of CD5+ B-LPDs and high sensitivity automated minimal residual disease quantitation of CLL/SLL.Cytometry. Part B, Clinical cytometry · 2021Article
- Observational
- Prevalence and Immunophenotypic Characteristics of Monoclonal B-Cell Lymphocytosis in Healthy Korean Individuals With Lymphocytosis.Annals of laboratory medicine · 2020Article
- Low-count monoclonal B-cell lymphocytosis persists after seven years of follow up and is associated with a poorer outcome.Haematologica · 2018Article
- Article
- Clonal evolution is a prognostic factor for the clinical progression of monoclonal B-cell lymphocytosis.Blood cancer journal · 2017Article
- Frequency of monoclonal B-cell lymphocytosis in relatives of patients with chronic lymphocytic leukemia.Colombia medica (Cali, Colombia) · 2016Article
- Prevalence of monoclonal B lymphocytosis in first-degree relatives of chronic lymphocytic leukemia patients in Turkey.Turkish journal of haematology : official journal of Turkish Society of Haematology · 2015Article
- Monoclonal B-cell lymphocytosis in healthy blood donors: an unexpectedly common finding.Blood · 2014Article
- Precursors to lymphoproliferative malignancies.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2013Review
- Article
- CLL-like B-lymphocytes are systematically present at very low numbers in peripheral blood of healthy adults.Leukemia · 2011Article
- Immunologic aspects of monoclonal B-cell lymphocytosis.Immunologic research · 2011Review
- The New Zealand black mouse as a model for the development and progression of chronic lymphocytic leukemia.Cytometry. Part B, Clinical cytometry · 2010Article
- Prevalence, clinical aspects, and natural history of IgM MGUS.Cytometry. Part B, Clinical cytometry · 2010Review
- Monoclonal B-cell lymphocytosis.Revista brasileira de hematologia e hemoterapiaArticle
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
backgroundIndividuals with monoclonal B-cell lymphocytosis (MBL) have been identified in clinic outpatients, in unaffected relatives of patients with chronic lymphocytic leukemia (CLL), and in general populations. MBL and its relationship with CLL have been actively investigated over the last decade. This report systematically reviews the prevalence of MBL in the context of the populations studied and the evolution of laboratory methods used to define MBL.
methodsTo identify published studies that have assessed the prevalence of MBL, we systematically searched the MEDLINE databases and consulted with members of the International MBL Study Group. We reviewed the 10 articles that were identified by this process. We abstracted information on study populations, laboratory tests, criteria for designating MBL, and the reported frequencies.
resultsThree of the ten studies were published in 2009, three between 2007 and 2008, and four between 2002 and 2004. Reported prevalences varied widely, ranging from 0.12 to 18.2%. This variability was clearly associated with both the laboratory methods and the populations studied. MBL was more common among older individuals and kindred of persons with CLL. The most common MBL subtype was CLL-like MBL.
conclusionsLarge population-based studies of MBL that employ standardized laboratory methods with a consensus case definition are needed to assess prevalence and establish risk factors. These studies should include prospective follow-up of MBL cases to determine the relationship between MBL and CLL. Data from original studies should be reported in sufficient detail to allow future synthesis of information from multiple studies, such as meta-analysis.
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