ArticleMedical microbiology and immunology2011
Monoassociation with probiotic Lactobacillus delbrueckii UFV-H2b20 stimulates the immune system and protects germfree mice against Listeria monocytogenes infection.
Article in Medical microbiology and immunology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 57 citations in OpenAlex.
- Genomic characterization and preclinical evaluation of the candidate probiotic strainFrontiers in microbiology · 2026Article
- Whole Genome Analysis ofAntibiotics (Basel, Switzerland) · 2025Article
- Article
- Oral administration of Lactobacillus delbrueckii UFV-H2b20 protects mice against Aspergillus fumigatus lung infection.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024Article
- The ProbioticMicroorganisms · 2023Article
- Clinically proven natural products, vitamins and mineral in boosting up immunity: A comprehensive review.Heliyon · 2023Review
- Modulatory Impacts of Multi-Strain Probiotics on Rabbits' Growth, Nutrient Transporters, Tight Junctions and Immune System to Fight againstAnimals : an open access journal from MDPI · 2022Article
- Resistance AgainstFrontiers in immunology · 2021Article
- Modulatory Effects of Probiotics During Pathogenic Infections With Emphasis on Immune Regulation.Frontiers in immunology · 2021Review
- Receptor-targeted engineered probiotics mitigate lethal Listeria infection.Nature communications · 2020Article
- A Comparison of Oral and Intravenous Mouse Models of Listeriosis.Pathogens (Basel, Switzerland) · 2018Review
- The multifaceted role of commensal microbiota in homeostasis and gastrointestinal diseases.Journal of immunology research · 2015Review
- Use of Probiotics to Control Aflatoxin Production in Peanut Grains.TheScientificWorldJournal · 2015Article
- Gut bacteria drive Kupffer cell expansion via MAMP-mediated ICAM-1 induction on sinusoidal endothelium and influence preservation-reperfusion injury after orthotopic liver transplantation.The American journal of pathology · 2013Article
- Regulation of bacterial pathogenesis by intestinal short-chain Fatty acids.Advances in applied microbiology · 2013Review
- Effects of Lactobacillus kefiranofaciens M1 isolated from kefir grains on germ-free mice.PloS one · 2013Article
- Impact of lactobacilli on orally acquired listeriosis.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Modern approaches in probiotics research to control foodborne pathogens.Advances in food and nutrition research · 2012Review
- Importance of IL-10 modulation by probiotic microorganisms in gastrointestinal inflammatory diseases.ISRN gastroenterology · 2011Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In the present study, we investigated the protective effects of Lactobacillus delbrueckii UFV-H2b20 on the resistance to Listeria monocytogenes infection in gnotobiotic mice. Germfree mice or monoassociated mice were infected with L. monocytogenes, and the microbiological and immunological responses were evaluated after 1, 3, and 5 days of infection. Monoassociation with L. delbrueckii was capable of protecting mice against death caused by L. monocytogenes and induced a faster clearance of the bacteria in the liver, spleen, and peritoneal cavity at days 1, 3, and 5 post-infection. Also, monoassociated mice displayed less liver injury than germfree mice. The production of TNF-α in the serum, peritoneal cavity, and gut was augmented in monoassociated mice. Likewise, the levels of IFN-γ found on supernatants of spleen cells cultures were higher after the monoassociation. In addition, increased production of nitric oxide in peritoneal cell cultures supernatants and in serum was observed in mice that received L. delbrueckii. The monoassociation with L. delbrueckii induced higher production of IL-10 in the mucosal immune system. We conclude that monoassociation with L. delbrueckii UFV-H2b20 protects mice from death caused by L. monocytogenes infection by favoring effector responses while preventing their immunopathological consequences.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.