ArticleNeuroreport2010
Regulation of vasoactive intestinal polypeptide release in the suprachiasmatic nucleus circadian clock.
Article in Neuroreport, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
22 citing papers in PubMed, 47 citations in OpenAlex.
- The Deubiquitinase USP2 Modulates Photic Entrainment of the Circadian Clock at the Level of the Suprachiasmatic Nucleus.Journal of neurochemistry · 2025Article
- A Journey in the Brain's Clock: In Vivo Veritas?Biology · 2023Review
- Light entrainment of the SCN circadian clock and implications for personalized alterations of corticosterone rhythms in shift work and jet lag.Scientific reports · 2021Article
- Vasopressin in circadian function of SCN.Journal of biosciences · 2020Review
- Suprachiasmatic function in a circadian period mutant: Duper alters light-induced activation of vasoactive intestinal peptide cells and PERIOD1 immunostaining.The European journal of neuroscience · 2018Article
- SCN VIP Neurons Are Essential for Normal Light-Mediated Resetting of the Circadian System.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2018Article
- Entrainment of Circadian Rhythms Depends on Firing Rates and Neuropeptide Release of VIP SCN Neurons.Neuron · 2018Article
- Differential regulation of nimodipine-sensitive and -insensitive CaJournal of biomedical science · 2018Article
- Photoperiod-Induced Neuroplasticity in the Circadian System.Neural plasticity · 2018Review
- Localization of photoperiod responsive circadian oscillators in the mouse suprachiasmatic nucleus.Scientific reports · 2017Article
- The dynamics of GABA signaling: Revelations from the circadian pacemaker in the suprachiasmatic nucleus.Frontiers in neuroendocrinology · 2017Review
- Circadian Plasticity of Mammalian Inhibitory Interneurons.Neural plasticity · 2017Review
- Collective timekeeping among cells of the master circadian clock.The Journal of endocrinology · 2016Review
- Distinct Firing Properties of Vasoactive Intestinal Peptide-Expressing Neurons in the Suprachiasmatic Nucleus.Journal of biological rhythms · 2016Article
- Role of Na⁺/Ca²⁺ exchanger in Ca²⁺ homeostasis in rat suprachiasmatic nucleus neurons.Journal of neurophysiology · 2015Article
- Molecular mechanisms that regulate the coupled period of the mammalian circadian clock.Biophysical journal · 2014Article
- Vasoactive intestinal polypeptide mediates circadian rhythms in mammalian olfactory bulb and olfaction.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Timing of neuropeptide coupling determines synchrony and entrainment in the mammalian circadian clock.PLoS computational biology · 2014Article
- A neuropeptide speeds circadian entrainment by reducing intercellular synchrony.Proceedings of the National Academy of Sciences of the United States of America · 2013Article
- The clock shop: coupled circadian oscillators.Experimental neurology · 2013Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
Abstract
Timing of the mammalian circadian clock of the suprachiasmatic nucleus (SCN) is regulated by photic input from the retina. Retinorecipient units entrain rhythmicity of SCN pacemaker cells in part through their release of vasoactive intestinal polypeptide (VIP). The underlying nature of this process is conjectural, however, as in-vivo SCN VIP release has never been measured. Here, SCN microdialysis was used to investigate mechanisms regulating VIP. Hamsters under light-dark cycle of 14:10 exhibited a daily peak in synaptic VIP release near midday. Under constant darkness, this output was arrhythmic. Light and the glutamatergic agonist, N-methyl-D-aspartate, stimulated VIP release at night, whereas the serotonin (1A,7) agonist, (±)8-hydroxy-2-(di-n-propylamino)tetralin hydrobromide, suppressed release at midday. Hence, SCN VIP activity is stimulated by photic input and inhibited by serotonin.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.