ReviewJournal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research2010
IGF-1 and bone: New discoveries from mouse models.
Review in Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 67 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 137 citations in OpenAlex.
- Bone-related adverse events of hormonal therapy: A pharmacovigilance study based on the Food & Drug Administration Adverse Event Reporting System.The Journal of international medical research · 2026Article
- HALP score-adjusted FRAXplus tool effectively predicts hip fracture risk in elderly women with type 2 diabetes mellitus.BMC endocrine disorders · 2026Article
- Fermented Oyster Extract Improves Linear Growth in Children with Idiopathic Short Stature: A Randomized, Double-Blind, Placebo-Controlled Trial.Preventive nutrition and food science · 2026Article
- The Role of IGF-1 and IL-10 in Childhood Stunting: Evidence From Indonesia.TheScientificWorldJournal · 2026Article
- Placental Igf1 overexpression sex-specifically impacts mouse placenta structure, altering offspring striatal development and behavior.Experimental neurology · 2025Article
- A head start: The relationship of placental factors to craniofacial and brain development.Developmental dynamics : an official publication of the American Association of Anatomists · 2025Review
- 24-Week jumping exercise influence on growth speed and GH-IGF-1-IGFBP-3 axis among short-stature children.BMC pediatrics · 2025Article
- Bone Tissue Engineering: From Biomaterials to Clinical Trials.Advances in experimental medicine and biology · 2025Review
- Review
- Article
- High-intensity interval training enhances mRNA expression of IGF1Ea in rat Achilles tendon.Molecular biology reports · 2024Article
- Molecular mechanisms underlying physical exercise-induced brain BDNF overproduction.Frontiers in molecular neuroscience · 2023Review
- CXCR4 mediates the effects of IGF-1R signaling in rodent bone homeostasis and fracture repair.Bone · 2023Article
- Bone loss is ameliorated by fecal microbiota transplantation through SCFA/GPR41/ IGF1 pathway in sickle cell disease mice.Scientific reports · 2022Article
- Growing Pains: The Need for Engineered Platforms to Study Growth Plate Biology.Advanced healthcare materials · 2022Review
- IGF-1 TMJ injections enhance mandibular growth and bone quality in juvenile rats.Orthodontics & craniofacial research · 2022Article
- Engineered Chimeric Peptides with IGF-1 and Titanium-Binding Functions to Enhance Osteogenic Differentiation In Vitro under T2DM Condition.Materials (Basel, Switzerland) · 2022Article
- A synonymous mutation inMolecular therapy. Nucleic acids · 2021Article
- Intra-iliac bone marrow injection as a novel alternative to intra-tibial inoculation in rat model.Stem cell research & therapy · 2021Article
- Gut-Bone Axis: A Non-Negligible Contributor to Periodontitis.Frontiers in cellular and infection microbiology · 2021Review
7 more citing papers are in PubMed but not listed here.
Corrections and comments
- Erratum issued
Authors and funding
3 authors at 2 institutions in 1 country.
Funding
Abstract
Insulin-like growth factor-1 (IGF-1) plays a central role in cellular growth, differentiation, survival, and cell cycle progression. It is expressed early during development and its effects are mediated through binding to a tyrosine kinase receptor, the insulin-like growth factor-1 receptor (IGF-1R). In the circulation, the IGFs bind to IGF-binding proteins (IGFBPs), which determine their bioavailability and regulate the interaction between the IGFs and IGF-1R. Studies in animal models and in humans have established critical roles for IGFs in skeletal growth and development. In this review we present new and old findings from mouse models of the IGF system and discuss their clinical relevance to normal and pathological skeletal physiology.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.