Evidence map›Paper›PMID 20835900›Full record

ReviewCurrent diabetes reports2010

Genetics of diabetes complications.

Alessandro Doria

Open access · greenAbstract readReview
In one paragraph

Review in Current diabetes reports, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 54 citations in OpenAlex.

  1. Trial
  2. Nanopore Sequencing ofACS omega · 2023
    Article
  3. Article
  4. Article
  5. Matrix Metalloproteinase-2 (Balkan journal of medical genetics : BJMG · 2022
    Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Genetic components in diabetic retinopathy.Indian journal of ophthalmology · 2016
    Article
  13. Review
  14. Review
  15. Article
  16. Genetics of diabetes complications.Mammalian genome : official journal of the International Mammalian Genome Society · 2014
    Review
  17. Article
  18. Type 2 Diabetes Genetics: Beyond GWAS.Journal of diabetes & metabolism · 2012
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Alessandro DoriaSection on Genetics & Epidemiology, Joslin Diabetes Center, One Joslin Place, Boston, MA 02215, USA. alessandro.doria@joslin.harvard.edu
Joslin Diabetes Center · US

Funding

SPECIAL ASSAY COREP30DK036836 · NIDDK · JOSLIN DIABETES CENTER · PI JEAN E. SCHAFFER · 1986 to 2026
$50.5M
Variability in Adipokine Genes and AtherosclerosisR01HL073168 · NHLBI · JOSLIN DIABETES CENTER · PI DORIA, ALESSANDRO · 2003 to 2012
$5.8M
Genetic Markers of CHD in Type 2 DiabetesR01HL071981 · NHLBI · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI QI, LU · 2003 to 2012
$4.9M
NHLBI NIH HHS HL71981NHLBI NIH HHS HL73168NHLBI NIH HHS R01 HL071981NHLBI NIH HHS R01 HL073168NIDDK NIH HHS DK36836NIDDK NIH HHS P30 DK036836
6 · The paper itself

Abstract

A large body of evidence indicates that the risk for developing chronic diabetic complications is under the control of genetic factors. Previous studies using a candidate gene approach have uncovered a number of genetic loci that may shape this risk, such as the VEGF gene for retinopathy, the ELMO1 gene for nephropathy, and the ADIPOQ gene for coronary artery disease. Recently, a new window has opened on identifying these genes through genome-wide association studies. Such systematic approach has already led to the identification of a major locus for coronary artery disease on 9p21 as well three potential genes for nephropathy on 7p, 11p, and 13q. Further insights are expected from a broader application of this strategy. It is anticipated that the identification of these genes will provide novel insights on the etiology of diabetic complications, with crucial implications for the development of new drugs to prevent the adverse effects of diabetes.

Indexed as

AnimalsAtherosclerosisCoronary Artery DiseaseDiabetes ComplicationsDiabetic NephropathiesDiabetic RetinopathyGenetic Predisposition to DiseaseHumansHyperglycemia

Identifiers

PMID20835900
PMCPMC2956847
OpenAlexW2163078441

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.