ArticleMolecular biology reports2011
Tamarix hispida metallothionein-like ThMT3, a reactive oxygen species scavenger, increases tolerance against Cd(2+), Zn(2+), Cu(2+), and NaCl in transgenic yeast.
Article in Molecular biology reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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18 citing papers in PubMed, 55 citations in OpenAlex.
- Transcriptomic Analysis of Cadmium StressedFrontiers in plant science · 2022Article
- Recent advances in physiological and molecular mechanisms of heavy metal accumulation in plants.Environmental science and pollution research international · 2021Review
- Article
- Transcription Factor GmWRKY142 Confers Cadmium Resistance by Up-Regulating the Cadmium Tolerance 1-Like Genes.Frontiers in plant science · 2020Article
- Identification of the metallothionein gene family from cucumber and functional characterization of3 Biotech · 2019Article
- Recent strategies of increasing metal tolerance and phytoremediation potential using genetic transformation of plants.Plant biotechnology reports · 2018Review
- Functional characterization of a type 2 metallothionein gene, SsMT2, from alkaline-tolerant Suaeda salsa.Scientific reports · 2017Article
- H₂O₂ Is Involved in the Metallothionein-Mediated Rice Tolerance to Copper and Cadmium Toxicity.International journal of molecular sciences · 2017Article
- Responses of Plant Proteins to Heavy Metal Stress-A Review.Frontiers in plant science · 2017Review
- Differential responses of three sweetpotato metallothionein genes to abiotic stress and heavy metals.Molecular biology reports · 2014Article
- Abiotic stress response in yeast and metal-binding ability of a type 2 metallothionein-like protein (PutMT2) from Puccinellia tenuiflora.Molecular biology reports · 2014Article
- Molecular cloning and characterisation of metallothionein type 2a gene from Jatropha curcas L., a promising biofuel plant.Molecular biology reports · 2014Article
- Two metallothionein genes in Oxya chinensis: molecular characteristics, expression patterns and roles in heavy metal stress.PloS one · 2014Article
- Heterologous expression and metal-binding characterization of a type 1 metallothionein isoform (OsMTI-1b) from rice (Oryza sativa).The protein journal · 2013Article
- The molecular mechanism of zinc and cadmium stress response in plants.Cellular and molecular life sciences : CMLS · 2012Review
- Overexpression of a heat shock protein (ThHSP18.3) from Tamarix hispida confers stress tolerance to yeast.Molecular biology reports · 2012Article
- Ycf1p attenuates basal level oxidative stress response in Saccharomyces cerevisiae.FEBS letters · 2012Article
- Heterologous expression of a rice metallothionein isoform (OsMTI-1b) in Saccharomyces cerevisiae enhances cadmium, hydrogen peroxide and ethanol tolerance.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology]Article
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5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A metallothionein-like gene, ThMT3, encoding a type 3 metallothionein, was isolated from a Tamarix hispida leaf cDNA library. Expression analysis revealed that mRNA of ThMT3 was upregulated by high salinity as well as by heavy metal ions, and that ThMT3 was predominantly expressed in the leaf. Transgenic yeast (Saccharomyces cerevisiae) expressing ThMT3 showed increased tolerance to Cd(2+), Zn(2+), Cu(2+), and NaCl stress. Transgenic yeast also accumulated more Cd(2+), Zn(2+), and NaCl, but not Cu(2+). Analysis of the expression of four genes (GLR1, GTT2, GSH1, and YCF1) that aid in transporting heavy metal (Cd(2+)) from the cytoplasm to the vacuole demonstrated that none of these genes were induced under Cd(2+), Zn(2+), Cu(2+), and NaCl stress in ThMT3-transgenic yeast. H(2)O(2) levels in transgenic yeast under such stress conditions were less than half those in control yeast under the same conditions. Three antioxidant genes (SOD1, CAT1, and GPX1) were specifically expressed under Cd(2+), Zn(2+), Cu(2+), and NaCl stress in the transgenic yeast. Cd(2+), Zn(2+), and Cu(2+) increased the expression levels of SOD1, CAT1, and GPX1, respectively, whereas NaCl induced the expression of SOD1 and GPX1.
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