Evidence map›Paper›PMID 20835801›Full record

ArticleMethods in molecular biology (Clifton, N.J.)2010

Protein quantitation using mass spectrometry.

Guoan Zhang, Beatrix M Ueberheide, Sofia Waldemarson, Sunnie Myung, Kelly Molloy, Jan Eriksson, Brian T Chait, Thomas A Neubert, David Fenyö

Abstract read
In one paragraph

Article in Methods in molecular biology (Clifton, N.J.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
13.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 72 citations in OpenAlex.

  1. MR-SPJournal of proteome research · 2026
    Article
  2. Mass Spectrometry for Proteomics-Based Investigation.Advances in experimental medicine and biology · 2026
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Quantitative Aspects of the Human Cell Proteome.International journal of molecular sciences · 2023
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Guoan ZhangKimmel Center for Biology and Medicine at the Skirball Institute and Department of Pharmacology, New York University School of Medicine, New York, NY, USA.
Beatrix M Ueberheide
Sofia Waldemarson
Sunnie Myung
Kelly Molloy
Jan Eriksson
Brian T Chait
Thomas A Neubert
David Fenyö
Rockefeller University · USNew York University · USSwedish University of Agricultural Sciences · SE

Funding

NEW TOOLS FOR EXPLORING THE DYNAMIC INTERACTOME(RMI)U54RR022220 · NCRR · ROCKEFELLER UNIVERSITY · PI ROUT, MICHAEL P · 2005 to 2011
$19.3M
YNG1 PHD BINDING TO H3 3METHYL AT K4 PROMOTES TRANSCRIPTION AT TARGETED ORFSP41RR000862 · NCRR · ROCKEFELLER UNIVERSITY · PI DARNELL, JAMES E · 1985 to 2011
$16.1M
Assessment of serum peptide profiling to detect cancer-specific patternsU24CA126485 · NCI · SLOAN-KETTERING INST CAN RESEARCH · PI TEMPST, PAUL · 2006 to 2010
$8.0M
Protein Mass Spectrometry Core Facility for NeuroscienceP30NS050276 · NINDS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI NEUBERT, THOMAS A · 2005 to 2015
$7.9M
NCI NIH HHS CA126485NCI NIH HHS U24 CA126485NCRR NIH HHS P41 RR000862NCRR NIH HHS RR00862NCRR NIH HHS RR022220NCRR NIH HHS U54 RR022220NINDS NIH HHS NS050276NINDS NIH HHS P30 NS050276
6 · The paper itself

Abstract

Mass spectrometry is a method of choice for quantifying low-abundance proteins and peptides in many biological studies. Here, we describe a range of computational aspects of protein and peptide quantitation, including methods for finding and integrating mass spectrometric peptide peaks, and detecting interference to obtain a robust measure of the amount of proteins present in samples.

Indexed as

Amino Acid SequenceIsotopesMass SpectrometryMolecular Sequence DataMolecular WeightPeptidesProteinsIsotopesPeptidesProteins

Identifiers

PMID20835801
PMCPMC3758905
OpenAlexW1475896266

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.