Evidence map›Paper›PMID 20835794›Full record

ReviewMethods in molecular biology (Clifton, N.J.)2010

Template-based protein structure modeling.

Andras Fiser

Abstract readReview
In one paragraph

Review in Methods in molecular biology (Clifton, N.J.), 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed.

  1. Chemical Profiling and Antimicrobial Activity of the Leaf Essential Oil ofInternational journal of molecular sciences · 2026
    Article
  2. Article
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  4. AnCurrent drug targets · 2026
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  9. Metformin-Driven Activation of Polymorphic Follicle-Stimulating Hormone Receptors for Polycystic Ovary Syndrome Treatment: A Computational Study.Medical science monitor : international medical journal of experimental and clinical research · 2025
    Article
  10. Review
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  17. Heliyon · 2024
    Article
  18. Article
  19. Discovery of a Novel Cellobiose Dehydrogenase fromJournal of microbiology and biotechnology · 2024
    Article
  20. Article

19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Andras FiserDepartment of Systems and Computational Biology, Albert Einstein College of Medicine, Bronx, NY, USA.

Funding

The NYSGRC: A Large Scale Center for PSI:BiologyU54GM094662 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI ALMO, STEVEN C. · 2010 to 2014
$32.6M
Membrane protein structure modeling with experimental restraintsR01GM096041 · NIGMS · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI FISER, ANDRAS · 2011 to 2014
$1.3M
NIGMS NIH HHS R01 GM096041NIGMS NIH HHS U54 GM094662
6 · The paper itself

Abstract

Functional characterization of a protein is often facilitated by its 3D structure. However, the fraction of experimentally known 3D models is currently less than 1% due to the inherently time-consuming and complicated nature of structure determination techniques. Computational approaches are employed to bridge the gap between the number of known sequences and that of 3D models. Template-based protein structure modeling techniques rely on the study of principles that dictate the 3D structure of natural proteins from the theory of evolution viewpoint. Strategies for template-based structure modeling will be discussed with a focus on comparative modeling, by reviewing techniques available for all the major steps involved in the comparative modeling pipeline.

Indexed as

Models, MolecularAmino Acid SequenceComputational BiologyInternetProteinsSequence AlignmentProteins

Identifiers

PMID20835794
PMCPMC4108304

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.