Evidence map›Paper›PMID 20835747›Full record

Trial reportInternational journal of public health2011

Hypertension and risk of death from external causes in the Physicians' Health Study enrollment cohort.

Paul D Terry, Robert J Glynn, Julie E Buring, Howard D Sesso

Abstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in International journal of public health, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 88% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Paul D TerryDepartment of Public Health, University of Tennessee, Knoxville, TN, USA. pdterry@utk.edu
Robert J Glynn
Julie E Buring
Howard D Sesso
Brigham and Women's Hospital · USUniversity of Tennessee at Knoxville · US

Funding

Physicians' Health Study II: Prevention Trial of VitaminsR01CA097193 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI GAZIANO, J. MICHAEL · 2002 to 2011
$15.7M
RANDOMIZED TRIAL OF ASPIRIN AND MORTALITYR01CA040360 · NCI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E · 1985 to 2002
$775k
TRIAL OF ASPIRIN AND BETA-CAROTENE IN U S MD'SR01HL034595 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E · 1985 to 1991
–
RANDOMIZED TRIAL OF MDS: STUDY OF LOW CV MORTALITYR01HL042441 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI BURING, JULIE E · 1990 to 1992
–
NCI NIH HHS CA-34944NCI NIH HHS CA-40360NCI NIH HHS CA-97193NCI NIH HHS R01 CA034944NCI NIH HHS R01 CA040360NCI NIH HHS R01 CA097193NHLBI NIH HHS HL-26490NHLBI NIH HHS HL-34595NHLBI NIH HHS HL-42441NHLBI NIH HHS R01 HL026490NHLBI NIH HHS R01 HL034595
6 · The paper itself

Abstract

objectivesTo address the recent hypothesis that hypertension increases the risk of death from external causes.

methodsWe examined blood pressure and death from external causes among 82,037 male physicians who were screened for eligibility to enroll in the Physicians' Health Study.

resultsDuring up to 6.6 years of mortality follow-up, there were 304 deaths from external causes. No association was found overall, although we observed an increased risk of non-passive external causes of death, particularly death due to falls, which was independent of various lifestyle, medical, and pharmacological risk factors.

conclusionsThe results of our study support this novel hypothesis. Further studies are needed to explore potential causal mechanisms between elevated BP and the risk of external death.

Indexed as

Cause of DeathHealthPhysiciansAdultAgedAged, 80 and overBlood PressureCohort StudiesConfounding Factors, EpidemiologicDeathDouble-Blind MethodFollow-Up StudiesHumansHypertensionMaleMiddle Aged

Identifiers

PMID20835747
PMCPMC3024448
OpenAlexW2051190387

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.