ArticleJournal of ocular biology, diseases, and informatics2009
Ocular disease in patients with ANCA-positive vasculitis.
Article in Journal of ocular biology, diseases, and informatics, 2009. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 74 citations in OpenAlex.
- Scleritis and associated systemic diseases: contribution of systemic examination, follow-up, and additional investigations.Journal of ophthalmic inflammation and infection · 2025Review
- Granulomatosis with polyangiitis presenting as axial proptosis and corneal perforation-a case report.BMC ophthalmology · 2025Article
- Recurrent strokes as the sole manifestation of antineutrophil cytoplasmic antibody associated vasculitis in a patientwith panuveitis: a case report.Journal of ophthalmic inflammation and infection · 2025Article
- A Comprehensive Review of Tubulointerstitial Nephritis and Uveitis (TINU) Syndrome.Biomedicines · 2025Review
- Visual Morbidity and Outcomes of Scleritis Associated with Intraocular Inflammation Compared to Isolated Scleritis.Ocular immunology and inflammation · 2024Article
- New Insights into Pathogenesis and Treatment of ANCA-Associated Vasculitis: Autoantibodies and Beyond.Antibodies (Basel, Switzerland) · 2023Review
- Ocular involvement in rheumatic diseases.Reumatologia · 2023Review
- Necrotizing Scleritis as a Manifestation of Eosinophilic Granulomatosis With Polyangiitis: A Case Report.Clinical medicine insights. Case reports · 2023Article
- Granulomatosis with Polyangiitis (GPA)-A Multidisciplinary Approach of a Case Report.Medicina (Kaunas, Lithuania) · 2022Article
- A Comprehensive Update on Retinal Vasculitis: Etiologies, Manifestations and Treatments.Journal of clinical medicine · 2022Review
- Choroidal involvement in systemic vasculitis: a systematic review.Journal of ophthalmic inflammation and infection · 2022Review
- Rituximab therapy combined with methotrexate for severe necrotizing scleritis in a case of granulomatosis with polyangiitis.Indian journal of ophthalmology · 2020Article
- Retinal artery occlusion followed by contralateral amaurosis fugax in association with eosinophilic granulomatosis with polyangiitis (Churg-Strauss syndrome).American journal of ophthalmology case reports · 2020Article
- More Than Meets the Eye: A Rare Case of Posterior Scleritis Masquerading as Orbital Cellulitis.Cureus · 2020Article
- Noninfectious Autoimmune Scleritis: Recognition, Systemic Associations, and Therapy.Current rheumatology reports · 2020Review
- Bilateral corneal perforation and iris prolapse as a complication non-peripheral ulcerative keratitis in a patient with fulminant granulomatosis with polyangiitis: a case report.Journal of ophthalmic inflammation and infection · 2020Article
- Clinical characteristics of scleritis patients with emphasized comparison of associated systemic diseases (anti-neutrophil cytoplasmic antibody-associated vasculitis and rheumatoid arthritis).Japanese journal of ophthalmology · 2019Article
- Relationship of ocular presentation in granulomatosis with polyangiitis to autoantibodies and disease activity.Zeitschrift fur Rheumatologie · 2019Article
- Peripheral Ulcerative Keratitis Associated with Granulomatosis with Polyangiitis Emerging Despite Cyclophosphamide, Successfully Treated with Rituximab.Internal medicine (Tokyo, Japan) · 2018Article
- Necrotising scleritis, keratitis and uveitis in primary antiphospholipid syndrome.BMJ case reports · 2018Article
Corrections and comments
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Authors and funding
14 authors at 8 institutions in 1 country.
Funding
Abstract
Anti-neutrophil cytoplasmic antibody (ANCA)-positive vasculitis-the term recently applied to Wegener's granulomatosis-is a rare multi-system inflammation characterized by necrotizing granulomas and vasculitis. We investigated the ocular manifestations of this disease in a group of patients drawn from five inflammatory eye disease clinics across the United States. Of 8,562 persons with ocular inflammation, 59 individuals were diagnosed with ANCA-positive vasculitis; 35 males and 21 females, aged 16 to 96 years, were included in this study. Ocular diagnoses were scleritis (75.0%), uveitis (17.9%), and other ocular inflammatory conditions (33.9%) including peripheral ulcerative keratitis and orbital pseudotumor. Mean duration of ocular disease was 4.6 years. Oral corticosteroids and other systemic immunosuppressive agents were used by 85.7% and 78.5% of patients, respectively. Over time, patients with ANCA-positive vasculitis experienced 2.75-fold higher mortality than other patients with inflammatory eye disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.