Evidence map›Paper›PMID 20833808›Full record

ArticleJournal of bacteriology2010

Latency of the lipid A deacylase PagL is involved in producing a robust permeation barrier in the outer membrane of Salmonella enterica.

Kiyoshi Kawasaki, Takayuki Manabe

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Journal of bacteriology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
  3. How the PhoP/PhoQ System Controls Virulence and MgMicrobiology and molecular biology reviews : MMBR · 2021
    Review
  4. Article
  5. Article
  6. D-form KLKLLLLLKLK-NHScientific reports · 2017
    Article
  7. Article
4 · The record

Corrections and comments

  • Erratum issued
5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Kiyoshi KawasakiFaculty of Pharmaceutical Sciences, Doshisha Women's College, Kyotanabe 610-0395, Japan. kkawasak@dwc.doshisha.ac.jp
Takayuki Manabe
Doshisha Women's College of Liberal Arts · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipid A deacylase PagL, which detoxifies endotoxin, is latent in Salmonella enterica. This study determined the biological significance of this latency. PagL latency was beneficial for bacteria in producing a robust permeation barrier through lipid A modifications under host-mimetic conditions that induced the modification enzymes, including PagL.

Indexed as

Anti-Bacterial AgentsBacterial Outer Membrane ProteinsBacterial ProteinsCarboxylic Ester HydrolasesDrug Resistance, Multiple, BacterialGene Expression Regulation, BacterialLipidsMicrobial Sensitivity TestsMolecular StructurePermeabilitySalmonella typhimuriumAnti-Bacterial AgentsBacterial Outer Membrane ProteinsBacterial ProteinsCarboxylic Ester HydrolasesLipidsPagL protein, Salmonella typhimurium

Identifiers

PMID20833808
PMCPMC2953691
OpenAlexW2143222786

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.