Evidence map›Paper›PMID 20833264›Full record

ReviewMutation research2010

Salvage of oxidized guanine derivatives in the (2'-deoxy)ribonucleotide pool as source of mutations in DNA.

Paul T Henderson, Mark D Evans, Marcus S Cooke

Abstract readReview
In one paragraph

Review in Mutation research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 31 citations in OpenAlex.

  1. Review
  2. The Role of Oxidative Stress in Kidney Injury.Antioxidants (Basel, Switzerland) · 2023
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Clinical Relevance of Biomarkers of Oxidative Stress.Antioxidants & redox signaling · 2015
    Review
  11. Salivary markers of oxidative stress in oral diseases.Frontiers in cellular and infection microbiology · 2015
    Review
  12. Article
  13. Review
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Paul T HendersonDivision of Hematology and Oncology, Department of Internal Medicine, University of California Davis Medical Center, 4501 X Street, Suite 3016, Sacramento, CA 95817, USA. paul.henderson@ucdmc.ucdavis.edu
Mark D Evans
Marcus S Cooke
University of Leicester · GBUniversity of California Davis Medical Center · US

Funding

VITAMIN C (ASCORBATE) METABOLISM IN DROSPHILA MELANOGASTERP41RR013461 · NCRR · UNIVERSITY OF CALIF-LAWRNC LVRMR NAT LAB · PI HASKELL, MARJORIE J · 1999 to 2011
$20.8M
NCRR NIH HHS P41 RR013461NCRR NIH HHS RR13461
6 · The paper itself

Abstract

Recent evidence suggests that salvage of 8-oxo-7,8-dihydro-2'-deoxyguanosine (8-oxodG) and 8-oxo-7,8-dihydro-guanine (8-oxoGua) can contribute substantially to levels of 8-oxoGua in DNA and RNA. However, it remains to be determined if this mechanism contributes to mutagenesis and disease. This review covers the predominant methods for detecting 8-oxoGua and its derivatives, summarizes some of the relevant recent DNA repair studies and discusses the mechanisms for metabolism of oxidized guanine derivatives in the (2'-deoxy)ribonucleoside and (2'-deoxy)ribonucleotide pools.

Indexed as

DNA DamageDNA RepairMutation8-Hydroxy-2'-DeoxyguanosineAnimalsDeoxyguanosineGuanineHumansOxidative Stress8-Hydroxy-2'-Deoxyguanosine8-hydroxyguanineDeoxyguanosineGuanine

Identifiers

PMID20833264
PMCPMC2991500
OpenAlexW2030807948

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.