ArticleTrends in cell biology2010
Dicing with dogma: de-branching the lamellipodium.
Article in Trends in cell biology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed.
- High Mobility Group Box 1 Promotes Lung Cancer Cell Migration and Motility via Regulation of Dynamin-Related Protein 1.International journal of molecular sciences · 2021Article
- The Chemosensory Function of Primary Cilia Regulates Cholangiocyte Migration, Invasion, and Tumor Growth.Hepatology (Baltimore, Md.) · 2019Article
- Ultrastructure of protrusive actin filament arrays.Current opinion in cell biology · 2013Review
- Role of molecular determinants of store-operated Ca(2+) entry (Orai1, phospholipase A2 group 6, and STIM1) in focal adhesion formation and cell migration.The Journal of biological chemistry · 2012Article
- Controlling the cortical actin motor.Protoplasma · 2012Review
- Impact of the carbazole derivative wiskostatin on mechanical stability and dynamics of motile cells.Journal of muscle research and cell motility · 2012Article
- Differences in adhesion and protrusion properties correlate with differences in migration speed under EGF stimulation.BMC biophysics · 2012Article
- Physical model for self-organization of actin cytoskeleton and adhesion complexes at the cell front.Biophysical journal · 2012Article
- The structure of cell-matrix adhesions: the new frontier.Current opinion in cell biology · 2012Review
- Walking to work: roles for class V myosins as cargo transporters.Nature reviews. Molecular cell biology · 2011Review
- Robust organizational principles of protrusive biopolymer networks in migrating living cells.PloS one · 2011Article
- Discussing the morphology of actin filaments in lamellipodia.Trends in cell biology · 2011Article
- Filopodia and adhesion in cancer cell motility.Cell adhesion & migrationReview
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1 author.
Funding
Abstract
The primary event in the movement of a migrating eukaryotic cell is the extension of cytoplasmic sheets termed lamellipodia composed of networks of actin filaments. Lamellipodia networks are thought to arise through the branching of new filaments from the sides of old filaments, producing a dendritic array. Recent studies by electron tomography have revealed the three dimensional organization of lamellipodia and show, contrary to previous evidence, that actin filaments do not form dendritic arrays in vivo. These findings signal a reconsideration of the structural basis of protrusion and about the roles of the different actin nucleating and elongating complexes involved in the process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.