Evidence map›Paper›PMID 20832881›Full record

ArticleTrends in biotechnology2010

Patently unpatentable: implications of the Myriad court decision on genetic diagnostics.

Mildred Cho

Abstract read
In one paragraph

Article in Trends in biotechnology, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. The New Precision Stewards?Journal of personalized medicine · 2022
    Article
  2. Research Translation and Emerging Health Technologies: Synthetic Biology and Beyond.Health care analysis : HCA : journal of health philosophy and policy · 2018
    Article
  3. Naked bodies, naked genomes: the special (but not exceptional) nature of genomic information.Genetics in medicine : official journal of the American College of Medical Genetics · 2015
    Review
  4. Review
  5. Gene patents: a broken incentives system.Journal of religion and health · 2013
    Review
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Mildred ChoStanford Center for Biomedical Ethics, 1215 Welch Road, Stanford, CA 94305, USA. micho@stanford.edu

Funding

Center for Integration of Research on Genetics and EthicsP50HG003389 · NHGRI · STANFORD UNIVERSITY · PI CHO, MILDRED K. · 2004 to 2014
$9.9M
EFFECTS OF GENE PATENTS ON GENETIC TESTING AND RESEARCHR01HG002034 · NHGRI · STANFORD UNIVERSITY · PI CHO, MILDRED K. · 2000 to 2002
$953k
NHGRI NIH HHS 1R01HG02034NHGRI NIH HHS 2P50HG003389NHGRI NIH HHS P50 HG003389NHGRI NIH HHS R01 HG002034
6 · The paper itself

Abstract

The recent decision in the case Association for Molecular Pathology et al. v. United States Patent and Trademark Office et al. shocked the biotechnology industry. Although the case could be overturned on appeal, it will probably change how gene patents are written. The effects of the decision might be most strongly felt in the short term by clinical laboratories that develop new genetic tests based on single genes. However, evidence suggests that patents are less effective as an incentive to innovate in the field of genetic diagnostics than for pharmaceuticals. In addition, as genomic technologies move towards whole-genome analysis, policy arguments for patent protection for single genes become less compelling. It is clear that the intellectual property model challenged by the Myriad decision will have to be replaced if new genetic technologies are to achieve their full potential in promoting 'the progress of science and useful arts'.

Indexed as

Genetic TechniquesHumansMolecular Diagnostic TechniquesPatents as TopicPathology, MolecularUnited States

Identifiers

PMID20832881
PMCPMC2955823

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.