Evidence map›Paper›PMID 20832500›Full record

ReviewMicrobes and infection2010

The immunoregulatory properties of oncolytic myxoma virus and their implications in therapeutics.

Jia Liu, Sonia Wennier, Grant McFadden

Open access · greenAbstract readReview
In one paragraph

Review in Microbes and infection, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 34 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Article
  7. Review
  8. Oncolytic Virotherapy with Myxoma Virus.Journal of clinical medicine · 2020
    Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Oncolytic Poxviruses.Annual review of virology · 2014
    Article
  15. Article
  16. Article
  17. Review
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jia LiuDepartment of Molecular Genetics and Microbiology, University of Florida College of Medicine, 1600 SW Archer Rd, P.O. box 100266, Gainesville, FL 32610, USA.
Sonia Wennier
Grant McFadden
University of Florida · US

Funding

Studies in Poxvirus Host Range Genes and TropismR01AI080607 · NIAID · UNIVERSITY OF FLORIDA · PI RAHMAN, MASMUDUR MOHAMMED · 2009 to 2025
$5.6M
Myxoma Virus (MV) Oncolysis for treating human cancerR01CA138541 · NCI · UNIVERSITY OF FLORIDA · PI MCFADDEN, GRANT · 2010 to 2014
$1.5M
NCI NIH HHS CA13854NCI NIH HHS R01 CA138541NIAID NIH HHS AI080607NIAID NIH HHS R01 AI080607
6 · The paper itself

Abstract

Myxoma virus (MYXV) is a poxvirus with a strict rabbit-specific host-tropism for pathogenesis. The immunoregulatory factors encoded by MYXV can suppress some functions of immune effectors from other species. We review their mechanisms of action, implications in therapeutics and the potential to improve MYXV as an oncolytic agent in humans.

Indexed as

AnimalsHumansImmunologic FactorsImmunotherapyMyxoma virusOncolytic VirusesRabbitsViral ProteinsImmunologic FactorsViral Proteins

Identifiers

PMID20832500
PMCPMC2998584
OpenAlexW2047763152

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.