ReviewCurrent opinion in neurobiology2011
Genetic dissection of axon regeneration.
Review in Current opinion in neurobiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The utilization of small non-mammals in traumatic brain injury research: A systematic review.CNS neuroscience & therapeutics · 2021Pooled it
- Review
- Article
- Review
- Functional Genome-wide Screen Identifies Pathways Restricting Central Nervous System Axonal Regeneration.Cell reports · 2018Article
- Homeostatic plasticity can be induced and expressed to restore synaptic strength at neuromuscular junctions undergoing ALS-related degeneration.Human molecular genetics · 2017Article
- The scales and tales of myelination: using zebrafish and mouse to study myelinating glia.Brain research · 2016Review
- Integrated analyses of zebrafish miRNA and mRNA expression profiles identify miR-29b and miR-223 as potential regulators of optic nerve regeneration.BMC genomics · 2015Article
- Axon-Schwann cell interactions during peripheral nerve regeneration in zebrafish larvae.Neural development · 2014Article
- Axon regeneration in C. elegans.Current opinion in neurobiology · 2014Review
- Neu3 sialidase-mediated ganglioside conversion is necessary for axon regeneration and is blocked in CNS axons.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Signaling pathways that regulate axon regeneration.Neuroscience bulletin · 2013Review
- PI3K-GSK3 signalling regulates mammalian axon regeneration by inducing the expression of Smad1.Nature communications · 2013Article
- Manipulating gene expression in projection-specific neuronal populations using combinatorial viral approaches.Current protocols in neuroscience · 2013Article
- Normal spastin gene dosage is specifically required for axon regeneration.Cell reports · 2012Article
- Regulation of DLK-1 kinase activity by calcium-mediated dissociation from an inhibitory isoform.Neuron · 2012Article
- Axon injury and stress trigger a microtubule-based neuroprotective pathway.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
- Neurite sprouting and synapse deterioration in the aging Caenorhabditis elegans nervous system.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2012Article
- Dynamics of degeneration and regeneration in developing zebrafish peripheral axons reveals a requirement for extrinsic cell types.Neural development · 2012Article
- Assembly of a new growth cone after axotomy: the precursor to axon regeneration.Nature reviews. Neuroscience · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Axon regeneration has long been studied in vertebrate model organisms and neuronal cultures. Recent development of axon regeneration paradigms in genetic model organisms, such as Caenorhabditis elegans, Drosophila and zebrafish, has opened an exciting field for in vivo functional dissection of regeneration pathways. Studies in these organisms have discovered essential genes and pathways for axon regrowth. The conservation of these genes crossing animal phyla suggests mechanistic relevance to higher organisms. The power of genetic approaches in these organisms makes large-scale genetic and pharmacological screens feasible and can greatly accelerate the mechanistic understanding of axon regeneration.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.