Evidence map›Paper›PMID 20832249›Full record

ArticleSchizophrenia research2010

The case for including Attenuated Psychotic Symptoms Syndrome in DSM-5 as a psychosis risk syndrome.

Scott W Woods, Barbara C Walsh, John R Saksa, Thomas H McGlashan

Open access · greenAbstract read
In one paragraph

Article in Schizophrenia research, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
10.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 122 citations in OpenAlex.

  1. Trial
  2. Glycine treatment of the risk syndrome for psychosis: report of two pilot studies.European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology · 2013
    Trial
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  4. Observational
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  6. Review
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  8. Full speed ahead on indicated prevention of psychosis.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2021
    Article
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  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Scott W WoodsConnecticut Mental Health Center, CT, USA. scott.woods@yale.edu
Barbara C Walsh
John R Saksa
Thomas H McGlashan
Connecticut Mental Health Center · USYale University · US

Funding

8/9 Predictors and Mechanisms of Conversion to PsychosisU01MH082022 · NIMH · YALE UNIVERSITY · PI WOODS, SCOTT W · 2008 to 2018
$6.0M
NIMH NIH HHS U01 MH082022
6 · The paper itself

Abstract

The American Psychiatric Association Task Force on DSM-5 has recently proposed consideration of Attenuated Psychotic Symptoms Syndrome as a new diagnosis, based on nearly 15 years of prospective research in centers across the globe. The condition is also known as "psychosis risk syndrome," "at-risk mental state," "ultra-high risk," and "putative prodrome." We review evidence favoring its inclusion as a new diagnosis in DSM-5 and report new preliminary findings on DSM-IV diagnoses in current clinical use for these patients and on results of diagnostic interviews in unselected volunteers. The main evidence supporting inclusion is: (1) the patients are currently ill, (2) the patients are at high risk for getting worse, (3) no DSM-IV diagnosis accurately captures their current illness or future risk, (4) the diagnosis has been made with reliability and validity in the research setting, and (5) placement in DSM-5 would help promote the needed treatment and prevention research to enable articulation of a standard of care to benefit these patients and their families. Potential harms can be minimized by patient, family, and provider education. It will be important to demonstrate through well-designed field trials whether the diagnostic criteria can be used with reliability in everyday clinical practice.

Indexed as

Diagnostic and Statistical Manual of Mental DisordersAdolescentAdultChildEarly DiagnosisFamilyFemaleHumansMaleMental DisordersPredictive Value of TestsPsychiatric Status Rating ScalesPsychotic DisordersReproducibility of ResultsRisk AssessmentSampling Studies

Identifiers

PMID20832249
PMCPMC3052695
OpenAlexW2026935634

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.