ArticleFrontiers in systems neuroscience2010
The Digital Bee Brain: Integrating and Managing Neurons in a Common 3D Reference System.
Article in Frontiers in systems neuroscience, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers.
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Who cites it
41 citing papers in PubMed, 93 citations in OpenAlex.
- Never underestimate honeybees: Their exceptionally diverse adaptive strategies.Journal of advanced research · 2026Review
- Age-related differences in learning, memory and brain plasticity in workers of the common wasp, Vespula vulgaris.The Journal of experimental biology · 2026Article
- Single-nucleus and spatial transcriptomics identify brain landscape of gene regulatory networks associated with behavioral maturation in honeybees.Nature communications · 2025Article
- Neuroecology of alcohol risk and reward: Methanol boosts pheromones and courtship success inScience advances · 2025Article
- Unique spatially and temporary-regulated/sex-specific expression of a long ncRNA, Nb-1, suggesting its pleiotropic functions associated with honey bee lifecycle.Scientific reports · 2024Article
- After 150 years of watching: is there a need for synthetic ethology?Animal cognition · 2023Review
- Illusional Perspective across Humans and Bees.Vision (Basel, Switzerland) · 2022Review
- In Search for the Retrievable Memory Trace in an Insect Brain.Frontiers in systems neuroscience · 2022Review
- Parallel mechanisms of visual memory formation across distinct regions of the honey bee brain.The Journal of experimental biology · 2021Article
- A reversal in sensory processing accompanies ongoing ecological divergence and speciation inProceedings. Biological sciences · 2021Article
- Using micro-computed tomography to reveal the anatomy of adult Diaphorina citri Kuwayama (Insecta: Hemiptera, Liviidae) and how it pierces and feeds within a citrus leaf.Scientific reports · 2021Article
- Neural Correlates of Social Behavior in Mushroom Body Extrinsic Neurons of the HoneybeeFrontiers in behavioral neuroscience · 2020Article
- Brain evolution in social insects: advocating for the comparative approach.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2019Review
- Planning of skull reconstruction based on a statistical shape model combined with geometric morphometrics.International journal of computer assisted radiology and surgery · 2018Article
- Exposure to a sublethal concentration of imidacloprid and the side effects on target and nontarget organs of Apis mellifera (Hymenoptera, Apidae).Ecotoxicology (London, England) · 2018Article
- In-situ recording of ionic currents in projection neurons and Kenyon cells in the olfactory pathway of the honeybee.PloS one · 2018Article
- Olfactory coding from the periphery to higher brain centers in the Drosophila brain.BMC biology · 2017Article
- Gene expression and immunohistochemical analyses of mKast suggest its late pupal and adult-specific functions in the honeybee brain.PloS one · 2017Article
- A Tyrosine-Hydroxylase Characterization of Dopaminergic Neurons in the Honey Bee Brain.Frontiers in systems neuroscience · 2017Article
- NBLAST: Rapid, Sensitive Comparison of Neuronal Structure and Construction of Neuron Family Databases.Neuron · 2016Article
Corrections and comments
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Authors and funding
9 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The honeybee standard brain (HSB) serves as an interactive tool for relating morphologies of bee brain neurons and provides a reference system for functional and bibliographical properties (http://www.neurobiologie.fu-berlin.de/beebrain/). The ultimate goal is to document not only the morphological network properties of neurons collected from separate brains, but also to establish a graphical user interface for a neuron-related data base. Here, we review the current methods and protocols used to incorporate neuronal reconstructions into the HSB. Our registration protocol consists of two separate steps applied to imaging data from two-channel confocal microscopy scans: (1) The reconstruction of the neuron, facilitated by an automatic extraction of the neuron's skeleton based on threshold segmentation, and (2) the semi-automatic 3D segmentation of the neuropils and their registration with the HSB. The integration of neurons in the HSB is performed by applying the transformation computed in step (2) to the reconstructed neurons of step (1). The most critical issue of this protocol in terms of user interaction time - the segmentation process - is drastically improved by the use of a model-based segmentation process. Furthermore, the underlying statistical shape models (SSM) allow the visualization and analysis of characteristic variations in large sets of bee brain data. The anatomy of neural networks composed of multiple neurons that are registered into the HSB are visualized by depicting the 3D reconstructions together with semantic information with the objective to integrate data from multiple sources (electrophysiology, imaging, immunocytochemistry, molecular biology). Ultimately, this will allow the user to specify cell types and retrieve their morphologies along with physiological characterizations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.