ArticleJournal of periodontal & implant science2010
Antioxidant profile of whole saliva after scaling and root planing in periodontal disease.
Article in Journal of periodontal & implant science, 2010. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 82 citations in OpenAlex.
- Meta-Analysis of Assessment of Total Oxidative Stress and Total Antioxidant Capacity in Patients with Periodontitis.Disease markers · 2023Pooled it
- The short-term effects of full-mouth or quadrant-wise applied subgingival instrumentation on immune response and oxidation process in saliva: a randomized clinical trial.BMC oral health · 2025Trial
- Micro-Raman spectroscopy for monitoring changes in periodontal ligaments and gingival crevicular fluid.Sensors (Basel, Switzerland) · 2014Trial
- Scaling-stimulated salivary antioxidant changes and oral-health behavior in an evaluation of periodontal treatment outcomes.TheScientificWorldJournal · 2014Trial
- Article
- Bacterial-host interactions in periodontal prognosis: Role ofJournal of dental sciences · 2026Article
- Hallmarks of Periodontitis.Current medicinal chemistry · 2025Review
- Article
- Article
- Periodontitis Continuum: Antecedents, Triggers, Mediators, and Treatment Strategies.Current medicinal chemistry · 2024Review
- Effect of Nonsurgical Periodontal Treatment on Salivary and Plasma Superoxide Dismutase Levels of Patients Suffering from Periodontitis.Journal of clinical medicine · 2023Article
- Does puberty affect oxidative stress levels and antioxidant activity of saliva in patients with fixed orthodontic appliances?Journal of orofacial orthopedics = Fortschritte der Kieferorthopadie : Organ/official journal Deutsche Gesellschaft fur Kieferorthopadie · 2023Article
- Antioxidant Effects of Curcumin Gel in Experimental Induced Diabetes and Periodontitis in Rats.BioMed research international · 2022Article
- Raman Spectroscopy: A Potential Diagnostic Tool for Oral Diseases.Frontiers in cellular and infection microbiology · 2022Review
- Anti-Inflammatory Potential of Complex Extracts ofAntioxidants (Basel, Switzerland) · 2021Article
- Associations between the phenotype and genotype of MnSOD and catalase in periodontal disease.BMC oral health · 2019Article
- A Cross-Sectional Study of Endogenous Antioxidants and Patterns of Dental Visits of Periodontitis Patients.International journal of environmental research and public health · 2019Article
- Effect of nonsurgical periodontal therapy on the level of salivary antioxidants in patients with generalized moderate-to-severe chronic periodontitis.Journal of advanced periodontology & implant dentistry · 2019Article
- Cigarette Smoking Aggravates the Activity of Periodontal Disease by Disrupting Redox Homeostasis- An Observational Study.Scientific reports · 2018Article
- Estimation of Antioxidant Levels in Saliva and Serum of Chronic Periodontitis Patients with and without Ischemic Heart Disease.International journal of dentistry · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study compared the total antioxidant status (TAS) and superoxide dismutase (SOD) activity in the saliva of periodontally compromised patients before and after scaling and root planing (SRP) to assess their diagnostic utility.
methodsSevere chronic periodontitis patient (test group) and subjects with no attachment loss, sites showing a 3 mm or more probing depth and a sulcus bleeding index < 10% (control group) were enrolled in this study. Saliva sampling and clinical examination were performed at one week, one month and 3 months after SRP. The TAS and SOD activity in each patient's saliva was measured for the comparative analysis between the groups.
resultsIn the test group, the TAS decreased directly after SRP. With time, it increased slightly and was relatively unchanged compared to the baseline. In the control group, the TAS also decreased immediately after SRP but increased gradually with time until 3 months. The SOD activity in the test and control subjects decreased immediately after SRP until 1 month. At 3 months, the SOD activity had increased. Both groups had a similar profile of SOD activity. However, the SOD activity of the control group was significantly higher than that of the test group at each point in time (P < 0.05).
conclusionsThere was a significant difference in the total salivary antioxidant level between the periodontitis and healthy or gingivitis (control) group during the experiment period. The total antioxidant level in the saliva was higher in the patients with severe chronic periodontitis than the healthy or gingivitis control before SRP. The SOD activity of the periodontitis patients was lower than the control at each time point. These findings conclusively reveal the possible use of saliva as a diagnostic tool for periodontal health.
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